Understanding the Genetic
Architecture of Parkinson's Disease

The Global Parkinson’s Genetics Program (GP2) is an ambitious program to genotype >150,000 volunteers around the world to further understand the genetic architecture of Parkinson’s disease (PD). There is still much to learn about genetic risk factors and the path to further understanding requires working collaboratively and openly sharing data, processes, and results.

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See how many samples are completed and shared with the AMP® PD platform for use.

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Collaborate with us and submit a cohort to GP2. 

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GP2 Updates

Check out the latest news about GP2.

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Expanded Data Available on GP2’s Updated Cohort Dashboard

September 6, 2022
The new cohort dashboard provides a real-time look at each cohort within the GP2 network, including location data, number of samples for genotyping, and an ancestral breakdown of completed samples.

Announcing GP2’s New Monogenic Resource Map

September 4, 2022
This online tool provides a look at data from GP2 or GP2-affiliated centers. Explore participant numbers, detailed clinical research and clinical trial activities and facilities for clinics focusing on monogenic Parkinson’s research.

Explore the Monogenic Portal

September 1, 2022
The Monogenic Portal gives researchers from around the globe a platform for sharing samples and key insights. Insights are focused on the studying early-onset cases of PD as well as cases with a family history, or atypical clinical presentations.

Latest Blog Posts

Read the latest blogs from GP2’s scientists and collaborators.

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Introduction to Using Workspaces and GP2 Data

September 2, 2022
The Terra cloud platform allows you to do analysis directly on the cloud, removing the need to download GP2 data directly to your personal computer. This blog is an introduction to analyzing GP2 Data on this platform using workspaces and notebooks.

New master’s trainees increase African representation in Parkinson's disease research

July 11, 2022
A big focus of GP2's work has been setting up PhD and MSc opportunities that will expand our reach and ensure that research capacity is generated where it is needed to further the understanding of the genetic basis of Parkinson’s disease (PD). Here, we share the stories of two successful trainees who are being supported through the Under-represented Populations Master’s Program.

The Components of GP2’s Second Data Release

May 20, 2022
In April 2022, GP2 announced the second data release on the Terra platform in collaboration with AMP® PD. This release contains data from both complex and monogenic GP2 networks. The complex disease data now consists of a total of 8,644 genotyped participants (5,249 PD, 3,395 non-PD).

Working Groups

Find out about GP2’s working groups and their recently accomplished milestones.

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