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Towards a Global View of Parkinson’s Disease Genetics

April 30, 2024

Training and Networking Working Group

10.1002/ana.26905

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Description

Parkinson’s disease (PD) is a global health challenge, yet historically studies of PD have taken place predominantly in European populations. Recent genetics research conducted in non-European populations has revealed novel population-specific genetic loci linked to PD risk, highlighting the importance of studying PD globally. These insights have broadened our understanding of PD etiology, which is crucial for developing disease-modifying interventions. This review comprehensively explores the global genetic landscape of PD, emphasizing the scientific rationale for studying underrepresented populations. It underscores challenges, such as genotype-phenotype heterogeneity and inclusion difficulties for non-European participants, emphasizing the ongoing need for diverse and inclusive research in PD. ANN NEUROL 2024;95:831-842.

Training and Networking Working Group

The Training and Networking working group promotes training and networking throughout the GP2 project.
Learn more about Training and Networking Working Group

Meet the authors

Postdoc

Marzieh Khany

National Institutes of Health (NIH) | Iran

Neurologist

Catalina Cleves

Laval University | Colombia

PhD , MSc

Mariam Kekenadze, MD, PhD

Tbilisi State Medical University/UCL | T'bilisi, Georgia

Postbaccalaureate IRTA Fellow

Peter Wild Crea

NIH | USA

Director

Andrew B Singleton, PhD

National Institute on Aging | Bethesda, MD, USA

Staff Scientist

Sara Bandres-Ciga, PharmD,PhD

National Institutes of Health | USA

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