The Global Parkinson’s Genetics Program (GP2) is a resource program of the Aligning Science Across Parkinson’s (ASAP) initiative focused on improving our understanding of the genetic architecture of Parkinson’s disease (PD) and making this knowledge globally relevant.
GP2 is made up of member organizations around the world that are coming together to create a global research community dedicated to rapidly addressing emerging research needs in PD. Our work is aimed at using genetics knowledge to accelerate the path to the development and deployment of therapeutic strategies for PD. Read below to learn about what we do.
GP2 aims to collect samples and data from around the world, specifically with the goal of including groups traditionally underrepresented in genetics research. GP2 works toward diversifying our understanding of PD by focusing on inclusion in the research pipeline. The program has assembled more than 100 cohorts from around the world with the ultimate goal of collecting and genotyping more than 150,000 unique samples, especially from diverse populations.
If you are interested in submitting a cohort and becoming a GP2 member or have any questions, please contact us at [email protected] and we will follow-up to learn more about you.
Building Global Will and Capacity
GP2 sets out to create a first-of-its-kind research community, orienting scientists all over the globe to GP2’s research mission. That community is bolstered by resources ranging from new clinics to training opportunities, especially in parts of the world traditionally underrepresented in PD research. For example, GP2’s online learning platform has already helped more than 700 individuals grow in the field, with courses covering everything from basic research techniques to complex genetic analyses.
Harmonizing and Analyzing Data
GP2 aims to create a discovery engine that generates a transformative understanding of the genetic basis of PD, complete with the global context that comes from including traditionally underrepresented populations. GP2 will make its wide swathes of data available to researchers all over the world through the online cloud computing platform AMP® PD. GP2 will perform core analyses and share findings through open-access channels, but qualified researchers are also encouraged to apply for direct access to the data.
Check out our dashboard to see our progress, learn about clinical sites ready for research, and more.
Looking for more?
Check out our resources page for additional information and guidance on generating resources.