Complex Disease – Cohort Integration analysis pipeline

“The Complex Disease – Cohort Integration Working Group (CIWG) aims to bring together clinical information and biosamples from 100,000 individuals with Parkinson’s disease (PD) who have donated their time and effort to help us understand and treat the disease.

We are assembling clinical and genetic data from eligible existing cohorts, as well as new cohorts of individuals with PD and healthy controls as part of the global collaboration. We have made great strides in PD research by comparing the genetic makeup of affected people with unaffected controls. This has enabled us to understand risk factor genes.

As part of this study we aim to understand variations between people with PD. For example, why some people progress slowly and some quickly and why some people develop side effects to medication and others have no problems. To understand this, we need to study genetic and clinical data together and we are collaborating with clinical cohorts worldwide to collate and study this data.”

Data and Code Dissemination Working Group

The Data and Code Dissemination working group works to enable open science by sharing meaningful data, analytical code, and results.
Learn more about Data and Code Dissemination Working Group

Meet the authors

Pre-doctoral Intramural Research Training Awardee

Mary B Makarious, BSc

National Institutes of Health | USA