Why study disease in different populations?

Although Latinos do have some European ancestry, this is highly variable in each person, even within the same country. In fact, fast-forwarding a few years, studies done on the patients of these same clinicians showed that the frequency of mutations in LRRK2 is highly linked to the amount of European ancestry that each country has on average, with countries like Peru that has the least amount of European genetic material, having the lowest frequency.

Underrepresented Populations Working Group

The Underrepresented Populations working group, facilitates increased representation and analysis of genetic factors associated with Parkinson’s disease in non-European populations.
Learn more about Underrepresented Populations Working Group

Meet the authors

Associate Staff, Assitant Professor

Ignacio (Nacho) F. Mata, PhD

Cleveland Clinic, Case Western Reserve University | Cleveland, OH, USA