Christian Lambert

I lead a research group focused anatomical phenomics, the link between differences in brain structure and phenotypic variability in health and disease. I am also a clinically active Consultant Neurologist based at the National Hospital for Neurology and Neurosurgery specialising in movement disorders. I am a member of the Methods group at the Wellcome Centre for Human Neuroimaging, and develop advanced computational techniques to map and study brain microstructure in vivo. I have technical expertise in a wide range of methods including quantitative MRI, deep phenotyping, computational anatomy, data clustering, machine learning and big data, coupled with clinical expertise in movement disorders and neurodegeneration. I am also a member of the UCL Queen Square Movement Disorder Centre.

I lead the “Quantitative MRI for Anatomical Phenotyping in Parkinson’s disease” study (qMAP-PD), a longitudinal observational study to better understand phenotypic variability in Parkinson’s disease. Through this, my aim is to develop tools that more accurately identify PD earlier, better anticipate disease trajectory, provide non-invasive quantitative biomarkers and help understand the mechanistic basis of disease variability at the individual subject level.