Andres Klein, PhD
Area of Focus
- Gaucher disease
- Lysosomes
- Genetic Modifiers
- Animal Models
- Gene mapping
- Gene-pesticide exposure interaction
- Gene prioritization
- Age at Onset
- Communications
- Collaboration
Biography
Andrés D. Klein, PhD, focuses his research on systems genetics and precision medicine, specifically investigating the molecular basis of phenotypic variability in lysosomal storage disorders (Gaucher, Niemann-Pick C, Pompe) and neurodegenerative conditions like Parkinson’s and Alzheimer’s by developing animal models to map modifier genes and therapeutic pathways followed by human validations. He completed B.Sc. in biochemistry and a PhD in Cellular and Molecular Biology at the Pontificia Universidad Católica de Chile, followed by postdoctoral training at Stanford University and the Weizmann Institute of Science. He was named a 2009–2011 Pew Latin American Fellow in the Biomedical Sciences and selected as one of the “100 Chilean young leaders” of 2013 by El Mercurio, and receiving the 2013 MIT Technology Review Innovators Under 35 award for his pioneering on the genetic basis of phenotypic variability in Gaucher’s disease. Recnetly he has been recognized as a top Chilean Scientific communicator in LinkedIn.