About GP2

The Global Parkinson’s Genetics Program (GP2) is a resource program for the Aligning Science Across Parkinson’s (ASAP) initiative focused on improving the understanding of the genetic architecture of Parkinson’s disease (PD) and making this knowledge globally relevant and accessible. 

GP2 is made up of working groups, member organizations, and investigators from around the world that come together to create a global research community dedicated to address emerging research needs for PD. Our work is aimed at using genetic knowledge to accelerate the path to the development and deployment of therapeutic strategies for PD. Read below to learn more about what we do. 

Collecting Samples

GP2 aims to collect samples and data from around the world, specifically with the goal of including groups traditionally underrepresented in genetics research. GP2 works toward diversifying our understanding of PD by focusing on inclusion in the research pipeline. The program has assembled over 220 cohorts from around the world with the ultimate goal of collecting and genotyping more than 250,000 unique samples, especially from diverse populations.

If you are interested in submitting a cohort and becoming a GP2 member or have any questions, please contact us and we will follow up to learn more about you.

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Building Global Will and Capacity

GP2 sets out to create a first-of-its-kind research community, orienting scientists all over the globe to GP2’s research mission. That community is bolstered by resources ranging from new clinics to training opportunities, especially in parts of the world traditionally underrepresented in PD research. For example, GP2’s online learning platform has already helped more than 700 individuals grow in the field, with courses covering everything from basic research techniques to complex genetic analyses. 

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Harmonizing and Analyzing Data 

GP2 aims to create a discovery engine that generates a transformative understanding of the genetic basis of PD, complete with the global context that comes from including traditionally underrepresented populations. GP2 makes its wide range of data available to researchers all over the world through the online cloud computing platform AMP® PD. GP2 performs core analyses and shares findings through open-access channels, but qualified researchers are also encouraged to apply for direct access to the data.

Check out our dashboard to see our progress, learn about clinical sites ready for research, and more.

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GP2 By the Numbers 

GP2 is progressing towards understanding the genetic architecture of PD through genotyping diverse participant groups and studying highly suspected monogenic forms of PD. Check out our interactive map to see our progress, learn about clinical sites ready for research, and more.

Explore Cohorts

227
Cohorts
More than
54K
Samples completed
More than
205K
Samples expected
76
Organizational Members

GP2 is a Global Collaborator

GP2 is developing tools, resources, workshops, and training opportunities to support the PD research community all over the globe.

More Than
50
Online Learning Sessions
Over
100
Working Group Members
Representing Over
60
Countries
More Than
900
Trainees

Explore GP2’s Blogs

Our blog posts provide key guidance, perspectives, and information that dives into GP2’s projects around the globe and offer additional resources to help the research community further understand the genetic architecture of PD. Check this section periodically to look for new blogs or sign up to get updates via email.

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I believe programs like this are crucial for advancing research and promoting inclusivity by shining a light on underrepresented populations and their research progress. The program created a great environment for sharing ideas and collaborating with people from a range of different backgrounds.