Helen Bateup, PhD

University of California, Berkeley

Helen S. Bateup completed her PhD with Dr. Paul Greengard at The Rockefeller University where she established genetic mouse models to determine the cell type-specific consequences of dopamine signaling on striatal-dependent behaviors. From there she joined Dr. Bernardo Sabatini’s lab as a postdoctoral fellow at Harvard Medical School where she elucidated how mutations associated with neurodevelopmental disorders affect synaptic function and network activity in the hippocampus. In 2013, Dr. Bateup started her lab at University of California, Berkeley in the Department of Molecular and Cell Biology where she is a member of the Helen Wills Neuroscience Institute. The goal of her research is to understand the cellular and molecular basis of neurodevelopmental and neurodegenerative disorders. To do this, her lab takes a multi-faceted approach utilizing genetic mouse models and human stem cell-derived brain organoids. Her work is defining how disease-associated genetic insults affect gene expression, signaling pathways, synaptic communication, and ultimately behavior.