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Alastair Noyce, MD, PhD

Queen Mary University of London

London, UK

Working Groups

Area of Focus

  • Epidemiology
  • Neurology

Biography

Alastair is a Professor in Neurology and Neuroepidemiology at the Preventive Neurology Unit in the Wolfson Institute of Preventive Medicine, Queen Mary University of London, and consultant neurologist at Barts Health NHS Trust, in the United Kingdom. Alastair graduated from Barts and the London School of Medicine and Dentistry in 2007. He pursued integrated training via the Foundation Academic Programme (2007-2009) and an NIHR Academic Clinical Fellowship at UCL (2009-2012). In 2012, he undertook a PhD in neuroscience at UCL. In 2016, he received an MSc in epidemiology at the London School of Hygiene and Tropical Medicine. His main research interests are Parkinson’s disease (PD) and related neurodegenerative disorders, particularly early identification and epidemiology, including environmental, clinical, and genetic determinants, in diverse populations.

Contact

[email protected]

Outputs and publications by Alastair Noyce, MD, PhD

The non-coding GBA1 rs3115534 variant is associated with REM sleep behavior disorder in Nigerians
Study in Nigerians links non-coding variant in GBA1 (rs3115534) to possible RBD, a feature of synucleinopathies like PD. Variant associated with RBD symptomatology in PD patients, suggesting similar effects as coding variants.
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Evaluating the performance of polygenic risk profiling across diverse ancestry populations in Parkinson’s disease
Study evaluates polygenic risk score models using 90 risk variants from 78 loci associated with Parkinson’s disease across seven ancestry groups to improve risk prediction accuracy and address disparities.
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