Data Resources

The Global Parkinson’s Genetics Program (GP2) is deeply committed to making science open, equipping a global research collective with the skill sets, tools, and infrastructure to rapidly and efficiently address emerging research needs and questions. Below is a snapshot summary of the GP2 resources that the community can leverage for their own research discovery.

Explore GP2's Data Resources

Global Activities Map
Within this interactive dashboard, view the cohorts involved within the GP2 network, including location, data, number of samples for genotyping, and an ancestral breakdown of completed samples shared with AMP® PD. You can also view the Monogenic Resource map, which highlights resources available from GP2 or GP2 affiliated centers, such as volume of patients seen in the clinic, detailed clinical research, and clinical trial activities.
GP2 Data Releases
Members of GP2’s Data Analysis Working Group release updated information every quarter on their progress towards genotyping over 250,000 volunteers. Each release provides an update on expected and completed samples as well as the ancestry breakdown of completed samples. These data releases are accompanied by a blog post that provides additional insights into each release.
Monogenic Portal
Focused on studying early-onset cases of Parkinson’s disease (PD), cases with a family history, or atypical clinical presentations, the Monogenic Portal offers a user-friendly, secure, web-based platform for the PD community. This allows researchers from around the globe to contribute and share samples and key insights. Users will need to register for access.
Interactive Browser for GWAS
We have partnered with the Broad Institute’s Association to Function Knowledge Portal alongside NIH’s Center for Alzheimer’s and Related Dementias (CARD) to share summary statistics for download and interactive visualization related to PD. This interactive results browser integrates genetic and genomic data across neurodegenerative disease to remove barriers for the interrogation of GP2 results.
GP2 GitHub
GP2 has its own repository on GitHub, GP2code, which follows best-practices and industry standards in open science code sharing. Please refer to GP2Code for more information and examples of GP2 projects that have been published or are currently being built within GitHub’s community-based framework.
Cohort Browser
The GP2 genetics browser facilitates the exploration of GP2's diverse population genetics dataset by researchers that do not write code. It allows you to explore multimodal data (genetic and clinico-demographic at this time) in context through its user-friendly graphical user interface. To access this tool and datasets, you must have an approved tier 2 GP2 data agreement in place.
Policies
GP2 is a program developed to support meaningful, multidisciplinary collaborations to tackle scientific challenges in PD. We are constantly generating documentation that provides guidance and a blueprint for other scientists and investigators around the world to adopt our framework.
GP2 Learning Platform
Training is central to the GP2 effort, and throughout this program we offer online training courses on a range of topics related to PD genetics. On a regular basis, different courses are added to the GP2 learning platform.
Outputs/Publications
GP2 is committed to ensuring the work of researchers is accessible to others. As part of our commitment to open access, we encourage you to explore these outputs.