{"id":50011997,"date":"2023-04-04T17:44:04","date_gmt":"2023-04-04T21:44:04","guid":{"rendered":"https:\/\/gp2stg.wpenginepowered.com\/gp2%e7%ac%ac%e5%9b%9b%e6%ac%a1%e6%95%b0%e6%8d%ae%e5%8f%91%e5%b8%83%e5%86%85%e5%ae%b9\/"},"modified":"2024-10-21T15:29:00","modified_gmt":"2024-10-21T19:29:00","slug":"gp2%e7%ac%ac%e5%9b%9b%e6%ac%a1%e6%95%b0%e6%8d%ae%e5%8f%91%e5%b8%83%e5%86%85%e5%ae%b9","status":"publish","type":"post","link":"https:\/\/gp2.org\/zh-hans\/gp2%e7%ac%ac%e5%9b%9b%e6%ac%a1%e6%95%b0%e6%8d%ae%e5%8f%91%e5%b8%83%e5%86%85%e5%ae%b9\/","title":{"rendered":"GP2\u7b2c\u56db\u6b21\u6570\u636e\u53d1\u5e03\u5185\u5bb9"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">2023\u5e742\u6708\uff0cGP2\u4e0eAMP<\/span><span style=\"font-weight: 400;\"><sup>\u00ae<\/sup><\/span><span style=\"font-weight: 400;\"> 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href=\"https:\/\/copn-rpco.ca\/\"><span style=\"font-weight: 400;\">\u52a0\u62ff\u5927\u5f00\u653e\u5e15\u91d1\u68ee\u7f51\u7edc(C-OPN)<\/span><\/a><span style=\"font-weight: 400;\">\uff0c\u8fd9\u662f\u7531\u4e5d\u6240\u52a0\u62ff\u5927\u5927\u5b66\u548c\u7814\u7a76\u4e2d\u5fc3\u7ec4\u6210\u7684\u5408\u4f5c\u7f51\u7edc<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u8fd0\u52a8\u969c\u788d\u7684\u57fa\u56e0\u578b\u548c\u8868\u578b&#8211;<\/span><a href=\"https:\/\/www.ed.ac.uk\/clinical-brain-sciences\/research\/edinburgh-brain-and-tissue-bank\"><span style=\"font-weight: 400;\">\u7231\u4e01\u5821\u8111\u5e93<\/span><\/a><span style=\"font-weight: 400;\">(MDGAP-EBB)\uff0c\u4e00\u5bb6\u6765\u81ea\u82f1\u56fd\u7684\u8111\u5e93<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/sbb.neura.edu.au\/\"><span style=\"font-weight: 400;\">\u6089\u5c3c\u8111\u5e93<\/span><\/a><span style=\"font-weight: 400;\">(SBB)\uff0c\u4e00\u5bb6\u603b\u90e8\u4f4d\u4e8e\u6fb3\u5927\u5229\u4e9a\u7684\u8111\u5e93<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 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wp-image-50006875 aligncenter\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-300x230.jpg\" alt=\"\" width=\"646\" height=\"495\" srcset=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-300x230.jpg 300w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-768x589.jpg 768w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-256x196.jpg 256w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-512x393.jpg 512w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1-939x720.jpg 939w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/04\/102049-010_GP2Blogs_DataChart_4_v192-1.jpg 1024w\" sizes=\"auto, (max-width: 646px) 100vw, 646px\" \/> <span style=\"font-weight: 400;\">\u672a\u6765\u7684\u6570\u636e\u53d1\u5e03\u8fd8\u5c06\u7ee7\u7eed\u63d0\u9ad8\u53c2\u4e0e\u8005\u7684\u591a\u5143\u6027\u3002\u60a8\u53ef\u4ee5\u5728<a href=\"https:\/\/gp2.org\/cohort-dashboard\/\">\u64cd\u4f5c\u9762\u677f<\/a>\u4e0a\u67e5\u770b\u6211\u4eec\u7684\u8fdb\u5c55<\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u6b64\u7248\u672c\u7684\u4e00\u4e2a\u91cd\u8981\u66f4\u65b0\u662f\u5bf9\u6211\u4eec\u7684QC\u6e20\u9053\u4e2d\u4f7f\u7528\u7684\u4e00\u4e2a\u9608\u503c\u8fdb\u884c\u4e86\u5fae\u8c03\u3002\u4e3a\u5206\u4eab\u66f4\u591a\u6837\u672c\uff0c\u6211\u4eec\u5df2\u5728\u5f00\u5c55QC\u6d41\u7a0b\u4e4b\u524d\u79fb\u9664\u4e86\u8d28\u91cf\u6301\u7eed\u4e0d\u4f73\u7684\u57fa\u56e0\u53d8\u5f02\u4f53\u3002\u5728Tier 2\u5b58\u50a8\u6876\u7684\u5143\u6570\u636e\u76ee\u5f55\u548c<a href=\"https:\/\/github.com\/GP2code\/releases\">Github<\/a><\/span><span style=\"font-weight: 400;\">\u4e0a\u53ef\u627e\u5230\u8868\u73b0\u8f83\u5dee\u7684\u53d8\u5f02\u4f53\u5217\u8868\u3002\u6211\u4eec\u8fd8\u91c7\u7528\u4e86\u4e0d\u592a\u4e25\u683c\u7684\u6837\u672c\u68c0\u51fa\u7387\uff0c\u4ece0.98\u964d\u4e3a0.95\u3002\u5982\u6b64\u4e00\u6765\uff0c\u4fbf\u80fd\u5728\u4e0d\u727a\u7272\u8d28\u91cf\u7684\u60c5\u51b5\u4e0b\u4f7f\u7528\u66f4\u591a\u7684\u6837\u54c1\u8fdb\u884c\u5206\u6790<\/span>\u3002<\/p>\n<p><span style=\"font-weight: 400;\">\u6b64\u7248\u672c\u7684\u53e6\u4e00\u5927\u66f4\u65b0\u662f\u5bf9\u4e34\u5e8a\u6570\u636e\u7684\u66f4\u65b0\u3002\u8868\u578b\u5217(\u201c\u8868\u578b\u201d)\u5df2\u66f4\u65b0\u4e3a\u6807\u7b7e\u201cPD\u7ec4\u201d\u3001\u201c\u63a7\u5236\u7ec4\u201d\u6216\u201c\u5176\u4ed6\u7ec4\u201d\u3002\u65b0\u589e\u7684\u2018\u5176\u4ed6\u8868\u578b\u2019\u4e00\u680f\uff0c\u4e3a\u53c2\u4e0e\u8005\u63d0\u4f9b\u4e86\u66f4\u8be6\u7ec6\u7684\u201c\u5176\u4ed6\u201d\u8bca\u65ad\u6807\u7b7e\u3002\u5176\u4e2d\u4e00\u4e9b\u66f4\u8be6\u7ec6\u7684\u8bca\u65ad\u6807\u7b7e\u5305\u62ec\u901a\u8fc7\u9776\u5411PD\u57fa\u56e0\u62db\u52df\u5230\u7684\u672a\u53d7\u5f71\u54cd\u548c\u53d7\u5f71\u54cd\u7684\u4e2a\u4eba\u3001SWEDDS\u548c\u524d\u9a71PD\uff0c\u4ee5\u53ca\u5176\u4ed6\u75be\u75c5\uff0c\u5982\u7279\u53d1\u6027\u9707\u98a4(ET)\u3001\u8fdb\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75f9(PSP)\u3001\u8def\u6613\u4f53\u75f4\u5446(DLB)\u548c\u591a\u7cfb\u7edf\u840e\u7f29(MSA)\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u6211\u4eec\u66f4\u65b0\u4e86\u6240\u6709\u901a\u8fc7\u8d28\u91cf\u63a7\u5236(\u57fa\u56e0\u6c34\u5e73\u52a0\u4e0a250kb\u4fa7\u7ffc\u533a\u57df)\u7684\u57fa\u56e0\u578b\u6837\u672c\u7684\u62f7\u8d1d\u6570\u53d8\u5f02(CNV)\u68c0\u51fa\uff0c\u4ee5\u56ca\u62ec\u7248\u672c4\u4e2d\u7684\u6240\u6709\u6837\u672c\u3002\u8be5\u6570\u636e\u5df2\u4f7f\u7528\u5b9a\u5236\u7684GP2\u57fa\u56e0\u578b\u805a\u7c7b\u6587\u4ef6\u8fdb\u884c\u4e86\u805a\u7c7b(\u53ef\u57281\u7ea7\u548c2\u7ea7\u6570\u636e\u8bbf\u95ee\u4e0b\u7684<\/span><b>utils<\/b><span style=\"font-weight: 400;\">\u76ee\u5f55\u4e2d\u67e5\u770b)\u3002\u7528\u4e8e\u9884\u6d4b\u6982\u7387CNV\u68c0\u51fa\u7684\u805a\u7c7b\u6587\u4ef6\u548c\u7ba1\u9053\u5747\u53ef\u5728<a href=\"https:\/\/github.com\/GP2code\">GP2 Github<\/a><\/span><span style=\"font-weight: 400;\">\u4e0a\u627e\u5230\uff0c\u53ef\u4e0eGP2\u4ee5\u5916\u7684\u6570\u636e\u4e00\u8d77\u4f7f\u7528\u3002\u6709\u5173\u4f7f\u7528\u5b9a\u5236\u7684GP2\u57fa\u56e0\u5206\u578b\u96c6\u7fa4\u6587\u4ef6\u548c\u62f7\u8d1d\u6570\u53d8\u91cf\u6982\u7387\u68c0\u6d4b\u8fdb\u884c\u805a\u7c7b\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u53c2\u9605GP2\u535a\u5ba2\u4e2d<\/span> <a href=\"https:\/\/gp2.org\/the-components-of-gp2s-third-data-release\/#:~:text=In%20October%202022%2C%20GP2%20announced,samples%20as%20the%20previous%20release.\">\u201cGP2\u7b2c\u4e09\u6b21\u6570\u636e\u53d1\u5e03\u5185\u5bb9\u201d<\/a><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u66f4\u591a\u5173\u4e8e\u590d\u6742\u75be\u75c5\u57fa\u56e0\u578b\u548c\u4e34\u5e8a\u6570\u636e\u8be6\u89c1\u9898\u4e3a<a href=\"https:\/\/gp2.org\/the-components-of-gp2-first-data-release\/\">\u201cGP2\u7b2c\u4e00\u6b21\u6570\u636e\u53d1\u5e03\u5185\u5bb9\u201d<\/a>\u2019 <\/span><span style=\"font-weight: 400;\">\u7684\u535a\u5ba2\u6587\u7ae0\uff0cREADME\u683c\u5f0f\u5df2\u6839\u636e\u672c\u6b21\u53d1\u5e03\u66f4\u65b0\uff0c\u53ef\u5728GP2\u5b98\u65b9Terra\u5de5\u4f5c\u7a7a\u95f4\u4e2d\u83b7\u53d6\u3002\u540c\u4e00\u4e2aREADME\u6587\u4ef6\u4e2d\u4e5f\u5305\u542b\u5355\u57fa\u56e0PD WGS\u6570\u636e\u7684\u8be6\u7ec6\u4fe1\u606f\u3002<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2023\u5e742\u6708\uff0cGP2\u4e0eAMP<sup>\u00ae<\/sup> PD\u4e00\u8d77\u5728Terra\u5e73\u53f0\u8fdb\u884c\u4e86\u7b2c\u56db\u6b21\u6570\u636e\u53d1\u5e03\u3002\u6b64\u6b21\u53d1\u5e03\u5305\u542b\u6d77\u91cf\u7684\u65b0\u6570\u636e\u548c\u65b0\u8d44\u6e90\u3002<\/p>\n","protected":false},"author":0,"featured_media":50024726,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50011997","post","type-post","status-publish","format-standard","hentry","post-type-gp2","post-type-751","post-type-743","topic-complex-disease-genetics-2","topic-research-collaboration-3","topic-research-operations-2","topic-762","topic-763","topic-764"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/posts\/50011997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/comments?post=50011997"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/posts\/50011997\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/media\/50024726"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/zh-hans\/wp-json\/wp\/v2\/media?parent=50011997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}