{"id":50012097,"date":"2024-01-18T18:21:59","date_gmt":"2024-01-18T23:21:59","guid":{"rendered":"https:\/\/gp2stg.wpenginepowered.com\/pd%e3%81%ae%e5%a4%9a%e7%a5%96%e5%85%88gwas\/"},"modified":"2024-10-21T15:49:16","modified_gmt":"2024-10-21T19:49:16","slug":"pd%e3%81%ae%e5%a4%9a%e7%a5%96%e5%85%88gwas","status":"publish","type":"post","link":"https:\/\/gp2.org\/ja\/pd%e3%81%ae%e5%a4%9a%e7%a5%96%e5%85%88gwas\/","title":{"rendered":"PD\u306e\u591a\u7956\u5148GWAS"},"content":{"rendered":"

\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\uff08PD\uff09\u306f\u5e83\u7bc4\u306a\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u7126\u70b9\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8005\u306f\u3001PD\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b90\u4ee5\u4e0a\u306e\u907a\u4f1d\u7684\u5909\u7570\u3092\u540c\u5b9a\u3057\u3001\u3053\u308c\u304c\u591a\u304f\u306e\u5206\u5b50\u7d4c\u8def\u304c\u95a2\u4e0e\u3059\u308b\u8907\u96d1\u306a\u75be\u60a3\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u00a0<\/span><\/p>\n

\u3057\u304b\u3057\u3001\u3088\u308a\u5e83\u3044\u8996\u91ce\u3067\u898b\u308b\u3068\u3001PD\u5efa\u4e45\u306f\u30e8\u30fc\u30ed\u30c3\u30d1\u306e\u7956\u5168\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u7269\u304c\u4e3b\u8981\u3067\u3042\u308a\u3001\u907a\u4f1d\u7684\u591a\u69d8\u6027\u304c\u6b20\u5982\u3057\u3066\u3044\u308b\u305f\u3081\u3001PD\u7814\u7a76\u306e\u4e16\u754c\u7684\u306a\u53d6\u308a\u7d44\u307f\u306f\u9032\u5c55\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3069\u306ePD\u907a\u4f1d\u5b50\u5909\u7570\u306b\u8d77\u56e0\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u96c6\u56e3\u9593\u3067\u81e8\u5e8a\u7684\u306b\u6709\u610f\u3068\u601d\u308f\u308c\u308b\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3069\u308c\u3067\u3057\u3087\u3046\u304b\uff1f<\/span>\u3053\u308c\u3089\u306e\u8cea\u554f\u306b\u7b54\u3048\u308b\u306b\u306f\u3001\u7956\u5148\u306e\u3088\u308a\u591a\u69d8\u306a\u30c7\u30fc\u30bf\u304c\u5fc5\u8981\u3067\u3059\u3002\u00a0<\/span><\/p>\n

\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\uff1a\u591a\u69d8\u306a\u7956\u5148\u3068\u5e83\u3044\u30b9\u30b1\u30fc\u30eb
\n<\/span><\/b>Nature Genetics<\/em>\u3067\u767a\u8868\u3055\u308c\u305f<\/a>\u65b0\u3057\u3044\u5171\u540c\u7814\u7a76\u306f\u3001PD\u306e\u907a\u4f1d\u7684\u30e9\u30f3\u30c9\u30b9\u30b1\u30fc\u30d7\u3092\u3088\u308a\u5305\u62ec\u7684\u304b\u3064\u30b0\u30ed\u30fc\u30d0\u30eb\u306b\u7406\u89e3\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u3053\u306e\u7814\u7a76\u306f\u3001<\/span>\u30b0\u30ed\u30fc\u30d0\u30eb\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u907a\u4f1d\u5b50\u30d7\u30ed\u30b0\u30e9\u30e0\uff08GP2<\/a>\uff09<\/span>\u304c\u4e3b\u5c0e\u3059\u308b\u4e16\u754c\u898f\u6a21\u306e\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\u3068\u30c7\u30fc\u30bf\u5171\u6709\u306e\u53d6\u308a\u7d44\u307f\u306b\u3088\u308b\u3068\u3053\u308d\u304c\u5927\u304d\u304f\u3001\u3053\u306e\u7a2e\u306e\u7814\u7a76\u3068\u3057\u3066\u306f\u6700\u5927\u898f\u6a21\u304b\u3064\u6700\u3082\u591a\u69d8\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001PD\u3092\u6301\u306449,049\u4eba\u3001\u4e21\u89aa\u304cPD\u3092\u6301\u3064\u307e\u305f\u306f\u6301\u3063\u3066\u3044\u305f18,785\u4eba\u3001\u304a\u3088\u3073\u30e8\u30fc\u30ed\u30c3\u30d1\u3001\u6771\u30a2\u30b8\u30a2\u3001\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u3001\u30a2\u30d5\u30ea\u30ab\u306e\u7956\u5148\u306e\u795e\u7d4c\u5b66\u7684\u306b\u5065\u5eb7\u306a200\u4e07\u4eba\u4ee5\u4e0a\u306e\u30c7\u30fc\u30bf\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

\u00a0<\/span>NIH\u3001GP2\u300123andMe\u306e\u7814\u7a76\u8005\u3068\u3001\u7c73\u56fd\u3001\u82f1\u56fd\u3001\u30da\u30eb\u30fc\u3001\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u306e\u5171\u540c\u7814\u7a76\u8005\u306f\u3001<\/span>FinnGen<\/span><\/a>\u3001<\/span><\/a>23andMe<\/span><\/a>\u3001<\/span><\/a>UK Biobank<\/span><\/a>\u3001\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306e\u30c7\u30fc\u30bf\u30ea\u30dd\u30b8\u30c8\u30ea\u304b\u3089\u3001\u3053\u306e\u7956\u5148\u7684\u306b\u591a\u69d8\u6027\u3092\u3082\u3064\u30c7\u30fc\u30bf\u3092\u30ad\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u30c7\u30fc\u30bf\u306b\u3088\u308a\u3001PD\u3068\u6709\u610f\u306b\u95a2\u9023\u306e\u3042\u308b78\u306e\u9818\u57df\uff08\u907a\u4f1d\u5b50\u5ea7\uff09\u3092\u7279\u5b9a\u3057\u307e\u3057\u305f\u3002\u00a0<\/span><\/p>\n

\u8907\u6570\u306e\u7570\u306a\u308b\u7956\u5148\u30b0\u30eb\u30fc\u30d7\u306e\u30c7\u30fc\u30bf\u3092\u5206\u6790\u3059\u308b\u306b\u306f\u56fa\u6709\u306e\u8ab2\u984c\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u591a\u69d8\u5316\u3059\u308b\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3059\u308b\u65b0\u3057\u3044\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u3084\u5206\u6790\u30c4\u30fc\u30eb\u304c\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30c4\u30fc\u30eb\u3068\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\u306e\u304a\u304b\u3052\u3067\u3001\u7814\u7a76\u8005\u306f\u8907\u6570\u306e\u7956\u5148\u30b0\u30eb\u30fc\u30d7\u306b\u3064\u3044\u3066PD\u30ea\u30b9\u30af\u3068\u6709\u610f\u306b\u95a2\u9023\u306e\u3042\u308b\u907a\u4f1d\u5b50\u9818\u57df\u3092\u7279\u5b9a\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u3088\u3046\u306a\u9818\u57df\u306f\u56e0\u679c\u7684\u5909\u7a2e\u3092\u542b\u3080\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\u7814\u7a76\u3067\u306f\u3001\u7814\u7a76\u8005\u3089\u306f\u591a\u7956\u5148\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\uff08GWAS\uff09\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3068\u547c\u3070\u308c\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u4f7f\u3044\u307e\u3057\u305f\u3002<\/span>GWAS<\/span><\/a>\u306f\u3001\u591a\u304f\u306e\u4eba\u306e\u30b2\u30ce\u30e0\u3092\u8abf\u67fb\u3059\u308b\u624b\u6cd5\u3067\u3001\u7279\u5b9a\u306e\u75be\u60a3\u3092\u6301\u3064\u4eba\u3068\u6301\u305f\u306a\u3044\u4eba\u3092\u6bd4\u8f03\u3057\u3066\u3001\u7279\u5b9a\u306e\u75be\u60a3\u3092\u6301\u3064\u4eba\u306b\u9ad8\u983b\u5ea6\u3067\u767a\u751f\u3059\u308b\u7279\u5b9a\u306e\u914d\u5217\u30d0\u30ea\u30a2\u30f3\u30c8\uff08\u300c\u907a\u4f1d\u5b50\u5ea7\u300d\uff09\u3092\u63a2\u3057\u307e\u3059\u3002\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001\u4ee5\u524d\u306b\u516c\u958b\u3055\u308c\u305fGWAS\u3068\u591a\u69d8\u306a\u30c7\u30fc\u30bf\u30ea\u30dd\u30b8\u30c8\u30ea\u304b\u3089\u30c7\u30fc\u30bf\u3092\u96c6\u3081\u3001PD\u306e\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u8981\u56e0\u306e\u63a2\u7d22\u306b\u7d71\u8a08\u5b66\u306e\u5a01\u529b\u3068\u5f37\u976d\u6027\u3092\u52a0\u3048\u307e\u3057\u305f\u3002\u00a0<\/span><\/p>\n

\u30e8\u30fc\u30ed\u30c3\u30d1\u4ee5\u5916\u306e\u4eba\u53e3\u7fa4\u306e\u30c7\u30fc\u30bf\u3092\u542b\u3081\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u7814\u7a76\u8005\u306f\u305d\u308c\u307e\u3067\u30e8\u30fc\u30ed\u30c3\u30d1\u304b\u3089\u6d3e\u751f\u3057\u305f\u4eba\u53e3\u7fa4\u3060\u3051\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u305f\u6642\u306b\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u591a\u304f\u306e\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u5ea7\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u3067\u540c\u5b9a\u3055\u308c\u305f78\u306ePD\u907a\u4f1d\u5b50\u5ea7\u306e\u5927\u534a\u306f\u65e2\u306bPD\u3068\u95a2\u9023\u306e\u3042\u308b\u9818\u57df\u3068\u4e00\u81f4\u3057\u307e\u3059\u304c\u3001\u305d\u306e\u3046\u3061\u306e12\u306f\u65b0\u898f\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u65b0\u898f\u306e\u907a\u4f1d\u5b50\u5ea7\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5206\u89e3\u3084\u4ee3\u8b1d\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6d3b\u52d5\u5236\u5fa1\u3001\u8133\u5185\u306e\u514d\u75ab\u5fdc\u7b54\u306a\u3069\u306b\u5f79\u7acb\u3064\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/span><\/p>\n

\u00a0<\/span>\u540c\u5b9a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u5ea7\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u30e8\u30fc\u30ed\u30c3\u30d1\u306e\u4eba\u53e3\u7fa4\u3092\u542b\u3080\u7814\u7a76\u3055\u308c\u305f\u3059\u3079\u3066\u306e\u7956\u5148\u306b\u308f\u305f\u3063\u3066PD\u30ea\u30b9\u30af\u3068\u6709\u610f\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u306f\u3001PD\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u591a\u304f\u306e\u7d4c\u8def\u304c\u96c6\u56e3\u9593\u3067\u5171\u6709\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\u500b\u5225\u5316\u533b\u7642\u306b\u5411\u3051\u3066\uff1a\u30d5\u30a1\u30a4\u30f3\u30de\u30c3\u30d4\u30f3\u30b0\u3068\u6a5f\u80fd\u7684\u610f\u7fa9
\n<\/span><\/b>\u7814\u7a76\u8005\u306f\u307e\u305f\u3001\u30d5\u30a1\u30a4\u30f3\u30de\u30c3\u30d4\u30f3\u30b0\u3068\u547c\u3070\u308c\u308b\u30d7\u30ed\u30bb\u30b9\u3067\u3001\u540c\u5b9a\u3057\u305f\u907a\u4f1d\u5b50\u5ea7\u306e\u5c11\u306a\u304f\u3068\u30826\u3064\u4ee5\u5185\u306b\u7279\u5b9a\u306e\u56e0\u679c\u7684\u907a\u4f1d\u7684\u5909\u7570\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u30d5\u30a1\u30a4\u30f3\u30de\u30c3\u30d4\u30f3\u30b0\u306f\u3001\u5404\u907a\u4f1d\u5b50\u5ea7\u5185\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306e\u3069\u308c\u304c\u3001\u7279\u5b9a\u306e\u4eba\u53e3\u7fa4\u306b\u304a\u3051\u308b\u75be\u75c5\u30ea\u30b9\u30af\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u304b\u3092\u63a8\u5b9a\u3057\u307e\u3059\u3002<\/span><\/p>\n

\u00a0<\/span>Learner Research Institute\u306e\u79d1\u5b66\u8005\u3001Cleveland Clinic Learner College of Medicine\u306e\u5206\u5b50\u533b\u5b66\u52a9\u6559\u6388\u3067\u3001\u3053\u306e\u7814\u7a76\u306e\u8457\u8005\u3067\u3042\u308b <\/span>\u30a4\u30b0\u30ca\u30b7\u30aa\u30fb\u30ca\u30c1\u30e7\u30fb \u30de\u30bf\u6c0f<\/span><\/a>\u306f\u3001\u300cGWAS\u306e\u8ab2\u984c\u306e1\u3064\u306f\u3001\u540c\u5b9a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u5ea7\u3067\u3001\u3069\u306e\u7279\u5b9a\u306e\u5909\u7570\u304c\u6a5f\u80fd\u7684\u5909\u7570\u306a\u306e\u304b\u3001\u56e0\u679c\u95a2\u4fc2\u306e\u3042\u308b\u5909\u7570\u306a\u306e\u304b\u304c\u308f\u304b\u3089\u306a\u3044\u3053\u3068\u3067\u3042\u308b\u300d\u300cGWAS\u306e\u30d2\u30c3\u30c8\u3001\u307e\u305f\u306f\u75be\u60a3\u3068\u6709\u610f\u306b\u95a2\u9023\u3059\u308b\u30b2\u30ce\u30e0\u306e\u9818\u57df\u3067\u306f\u3001\u4f55\u767e\u3082\u306e\u6f5c\u5728\u7684\u306a\u5909\u7570\u5019\u88dc\u304c\u5b58\u5728\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u300d\u3068\u8a71\u3057\u3066\u3044\u307e\u3059\u3002\u00a0<\/span><\/p>\n

\u00a0<\/span>\u200b<\/span>\u91cd\u8981\u306aGWAS\u907a\u4f1d\u5b50\u5ea7\u306b\u304a\u3051\u308b\u6a5f\u80fd\u30d0\u30ea\u30a2\u30f3\u30c8\u306e\u540c\u5b9a\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u3078\u306e\u5f71\u97ff\u306f\u3001PD\u306e\u8ffd\u8de1\u8abf\u67fb\u3068\u6a19\u7684\u6cbb\u7642\u85ac\u306e\u958b\u767a\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\u30ca\u30c1\u30e7\u6c0f\u306f\u307e\u305f\u3001\u300c\u5148\u7956\u4f1d\u6765\u306e\u591a\u69d8\u306a\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u3092\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3067\u3001\u540c\u5b9a\u3057\u305f\u907a\u4f1d\u5b50\u5ea7\u306e\u4e00\u90e8\u306e\u6a5f\u80fd\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u7d5e\u308a\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u305f\u300d\u300c\u5148\u7956\u4f1d\u6765\u306e\u591a\u69d8\u306a\u30c7\u30fc\u30bf\u3092\u4f7f\u3063\u3066\u3001\u305f\u3068\u3048\u3070\u6bcd\u96c6\u56e3\u306b\u56fa\u6709\u306e\u6f5c\u5728\u7684\u5909\u7570\u7a2e\u3092\u7279\u5b9a\u3067\u304d\u305f\u308a\u3001\u7570\u306a\u308b\u6bcd\u96c6\u56e3\u9593\u3067\u6709\u610f\u3067\u3042\u308b\u3001\u3057\u305f\u304c\u3063\u3066\u91cd\u8981\u306a\u56e0\u679c\u7684\u5371\u967a\u56e0\u5b50\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u5909\u7570\u7a2e\u3092\u7279\u5b9a\u3067\u304d\u308b\u300d\u3068\u8a71\u3057\u3066\u3044\u307e\u3059\u3002\u00a0<\/span><\/p>\n

\u540c\u5b9a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u5ea7\u306e\u3044\u304f\u3064\u304b\u306f\u3001\u7570\u306a\u308b\u96c6\u56e3\u9593\u3067\u7570\u306a\u308b\u5f71\u97ff\u3092\u793a\u3057\u3001\u7956\u5148\u56fa\u6709\u306e\u5371\u967a\u56e0\u5b50\u3092\u6398\u308a\u4e0b\u3052\u308b\u907a\u4f1d\u5b66\u7814\u7a76\u306e\u91cd\u8981\u6027\u304c\u6d6e\u304d\u5f6b\u308a\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u3068\u30a2\u30d5\u30ea\u30ab\u306e\u4eba\u53e3\u7fa4\u306e\u307f\u3067\u898b\u3064\u304b\u3063\u305f2\u3064\u306e\u907a\u4f1d\u5b50\u5ea7\u306f\u3001<\/span>JAK1<\/span><\/i>\u3068<\/span>HS1BP3<\/span><\/i>\u907a\u4f1d\u5b50\u306e\u8fd1\u304f\u306b\u3042\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u3069\u3061\u3089\u3082\u708e\u75c7\u30b7\u30b0\u30ca\u30eb\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001PD\u306b\u304a\u3051\u308b\u708e\u75c7\u306e\u5f79\u5272\u306b\u95a2\u308f\u3063\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\u793a\u5506\u3068\u4eca\u5f8c\u306e\u65b9\u5411\u6027<\/span><\/b>
\n<\/span>\u3053\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306b\u591a\u69d8\u306a\u7956\u5148\u3092\u542b\u3081\u308b\u3053\u3068\u306e\u91cd\u8981\u6027\u3092\u5f37\u8abf\u3057\u3066\u3044\u307e\u3059\u3002\u5305\u62ec\u6027\u306f\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u4e88\u6e2c\u306e\u7cbe\u5ea6\u3092\u9ad8\u3081\u3001\u500b\u5225\u5316\u6cbb\u7642\u306e\u767a\u5c55\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002GP2\u306f\u3001\u3042\u307e\u308a\u7814\u7a76\u3055\u308c\u3066\u3053\u306a\u304b\u3063\u305f\u4eba\u53e3\u7fa4\u3068\u5354\u529b\u3059\u308b\u6a5f\u95a2\u3068\u63d0\u643a\u3057\u3001\u4e16\u754c\u4e2d\u3067\u4e0d\u8db3\u3057\u3066\u3044\u308b\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306e\u30c7\u30fc\u30bf\u3092\u751f\u6210\u3057\u3066\u3044\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\u30ca\u30c1\u30e7\u6c0f\u306f\u3001\u300c\u4e16\u754c\u4e2d\u306e\u4eba\u3005\u304c\u5354\u529b\u3057\u3001\u4e92\u3044\u306b\u5b66\u3073\u5408\u3063\u3066\u3044\u305f\u300d\u300c\u79c1\u306b\u3068\u3063\u3066\u3001\u3053\u306e\u5171\u540c\u7814\u7a76\u306f\u3001\u7814\u7a76\u3068\u5c06\u6765\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u4e00\u756a\u672c\u5f53\u30ef\u30af\u30ef\u30af\u3055\u305b\u3089\u308c\u308b\u3082\u306e\u3060\u300d\u3068\u8a9e\u308a\u307e\u3057\u305f\u3002<\/span>\u00a0<\/span><\/p>\n

\u3053\u306e\u7814\u7a76\u3067\u7279\u5b9a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u5ea7\u304cPD\u7d4c\u8def\u3084\u75be\u60a3\u767a\u73fe\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u53d6\u308a\u7d44\u307f\u306f\u4eca\u5f8c\u306e\u7814\u7a76\u306e\u57fa\u790e\u3068\u306a\u308b\u5f37\u56fa\u306a\u57fa\u76e4\u3068\u306a\u308a\u307e\u3059\u3002<\/span>\u00a0<\/span><\/p>\n

\"\"<\/p>\n

\u3053\u306e\u53d6\u308a\u7d44\u307f\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u305f\u306e\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\uff1a\u30a2\u30e1\u30ea\u30ab\u56fd\u7acb\u885b\u751f\u7814\u7a76\u6240\uff08NIH \uff09 \u3001 \u56fd\u7acb\u8001\u5316\u7814\u7a76\u6240\uff08NIA \uff09 \u3001 NIH\u3001\u4fdd\u5065\u798f\u7949\u7701\u3001\u56fd\u7acb\u795e\u7d4c\u75be\u60a3\u30fb\u8133\u5352\u4e2d\u7814\u7a76\u6240\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u8ca1\u56e3\u3001\u30de\u30a4\u30b1\u30eb\u30fbJ\u30fb\u30d5\u30a9\u30c3\u30af\u30b9\u8ca1\u56e3\u3001Aligning Science Across Parkinson’s Global Parkinson\u2019s Genetic Project\uff08ASAP-GP2 \uff09 \u3001 \u30a2\u30e1\u30ea\u30ab\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u5354\u4f1a\u3001National Medical Research Council Singapore\u3001\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u6559\u80b2\u7701\u5b66\u8853\u7814\u7a76\u57fa\u91d1\u306e\u5b66\u969b\u7814\u7a76\u30d7\u30ed\u30b0\u30e9\u30e0\u3002<\/span><\/i><\/p>\n

\u00a0<\/span><\/i>\u3053\u306e\u8abf\u67fb\u306f\u3001\u7533\u8acb\u756a\u53f733601\u306e\u82f1\u56fd\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u30ea\u30bd\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3066\u884c\u308f\u308c\u307e\u3057\u305f\u3002FinnGen\u7814\u7a76\u306e\u53c2\u52a0\u8005\u3068\u7814\u7a76\u8005\u306b\u611f\u8b1d\u3092\u7533\u3057\u4e0a\u3052\u307e\u3059\u3002\u7814\u7a76\u53c2\u52a0\u8005\u306823andMe\u306e\u793e\u54e1\u306b\u3082\u611f\u8b1d\u81f4\u3057\u307e\u3059\u3002\u3053\u306e\u8a18\u4e8b\u3067\u4f7f\u7528\u3055\u308c\u305f\u30c7\u30fc\u30bf\u306f\u3001Global Parkinson\u2019s Genetics Program (GP2) \u304b\u3089\u53d6\u5f97\u3055\u308c\u307e\u3057\u305f\u3002GP2\u306f\u3001Aligning Science Against Parkinson\u2019s (ASAP\uff09\u30a4\u30cb\u30b7\u30a2\u30c1\u30d6\u3088\u308a\u8cc7\u91d1\u3092\u53d7\u3051\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u7814\u7a76\u306e\u30de\u30a4\u30b1\u30eb\u30fbJ\u30fb\u30d5\u30a9\u30c3\u30af\u30b9\u8ca1\u56e3\u306b\u3088\u3063\u3066\u5b9f\u65bd\u3055\u308c\u3066\u3044\u307e\u3059 (<\/span><\/i>https:\/\/gp2.org<\/span><\/i><\/a>\uff09\u3002<\/span><\/i><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\uff08PD\uff09\u306f\u5e83\u7bc4\u306a\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u7126\u70b9\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8005\u306f\u3001PD\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b90\u4ee5\u4e0a\u306e\u907a\u4f1d\u7684\u5909\u7570\u3092\u540c\u5b9a\u3057\u3001\u3053\u308c\u304c\u591a\u304f\u306e\u5206\u5b50\u7d4c\u8def\u304c\u95a2\u4e0e\u3059\u308b\u8907\u96d1\u306a\u75be\u60a3\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u00a0 \u3057 […]<\/p>\n","protected":false},"author":0,"featured_media":50024649,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50012097","post","type-post","status-publish","format-standard","hentry","post-type-741","post-type-722","topic-research-collaboration-6","topic-research-operations-3","topic---4","topic---2"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50012097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/comments?post=50012097"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50012097\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media\/50024649"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media?parent=50012097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}