{"id":50012017,"date":"2023-05-09T22:06:02","date_gmt":"2023-05-10T02:06:02","guid":{"rendered":"https:\/\/gp2stg.wpenginepowered.com\/gp2%e7%ac%ac5%e5%9b%9e%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9\/"},"modified":"2024-10-21T15:32:43","modified_gmt":"2024-10-21T19:32:43","slug":"gp2%e7%ac%ac5%e5%9b%9e%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9","status":"publish","type":"post","link":"https:\/\/gp2.org\/ja\/gp2%e7%ac%ac5%e5%9b%9e%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9\/","title":{"rendered":"GP2\u7b2c5\u56de\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u306e\u5185\u5bb9"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">\uff12\uff10\uff12\uff13\u5e74\uff15\u6708\u306bGP\uff12\u306fAMP<\/span><span style=\"font-weight: 400;\">\u00ae<\/span><span style=\"font-weight: 400;\"> PD<\/span>\u3068\u306e\u5354\u529b\u306e\u3082\u3068Terra\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306b\u304a\u3044\u3066\u7b2c\u4e94\u56de\u76ee\u306e\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u3092\u884c\u3063\u305f\u3053\u3068\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><span style=\"font-weight: 400;\">\u672c\u30ea\u30ea\u30fc\u30b9\u306b\u306f\u30017462\u4eba\u306e\u8907\u5408\u75be\u60a3\u53c2\u52a0\u8005\u3068\u3001487\u4eba\u306e\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u53c2\u52a0\u8005\u304c\u65b0\u305f\u306b\u8ffd\u52a0\u3055\u308c\u3001\u8907\u5408\u30fb\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304b\u3089\u306e\u3053\u308c\u307e\u3067\u30ea\u30ea\u30fc\u30b9\u306b\u8ffd\u52a0\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>\u8907\u5408\u75be\u60a3\u30c7\u30fc\u30bf\uff08\u907a\u4f1d\u5b50\u578b\uff09\u306f\u73fe\u5728\u3001\u5408\u8a08<\/b><b>24935\u540d<\/b><b>\u306e\u907a\u4f1d\u5b50\u578b\u540c\u5b9a\u53c2\u52a0\u8005(PD12728\u4eba<\/b><b>\u3001\u5bfe\u7167\u7fa410533\u4eba\u3001\u305d\u306e\u4ed61674\u4eba)\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3\u30c7\u30fc\u30bf\uff08\u5168\u30b2\u30ce\u30e0\u914d\u5217\uff09\u306f\u3001\u73fe\u5728\u3001\u8a08722\u4eba\u306e\u914d\u5217\u540c\u5b9a\u3055\u308c\u305f\u53c2\u52a0\u8005\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/b><\/li>\n<\/ul>\n<p><b>\u500b\u4eba\u30ec\u30d9\u30eb\u30c7\u30fc\u30bf\uff1a<\/b><span style=\"font-weight: 400;\">\u672c\u30ea\u30ea\u30fc\u30b9\u3067GP2\u306b\u8ffd\u52a0\u3055\u308c\u305f\u65b0\u3057\u3044\u30b3\u30db\u30fc\u30c8\u306f\u6b21\u306e\u901a\u308a\u3067\u3059\uff1a<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30a2\u30ea\u30be\u30ca\u30d6\u30ec\u30a4\u30f3\u30d0\u30f3\u30af\u3000\u8133\u3068\u8eab\u4f53\u5bc4\u4ed8\u30d7\u30ed\u30b0\u30e9\u30e0\uff08BBDP\uff09\u3001\u7c73\u56fd\u3092\u62e0\u70b9\u3068\u3059\u308b\u30d6\u30ec\u30a4\u30f3\u30d0\u30f3\u30af<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306b\u304a\u3051\u308b\u81ea\u7136\u514d\u75ab\u3068\u9069\u5fdc\u514d\u75ab\uff08IMMUNEPD\uff09\u3001\u30a2\u30e9\u30d0\u30de\u5927\u5b66\u30d0\u30fc\u30df\u30f3\u30ac\u30e0\u6821\u306e\u7c73\u56fd\u30d9\u30fc\u30b9\u306e\u7814\u7a76<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">IPDGC\u30a2\u30d5\u30ea\u30ab\uff08IPDGCAF-NG\uff09\u3001\u30ca\u30a4\u30b8\u30a7\u30ea\u30a2\u306e\u30b3\u30db\u30fc\u30c8<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">PDGENEration \uff08PDGNRTN\uff09\u3001<\/span><strong><a href=\"https:\/\/www.parkinson.org\/\" target=\"_blank\" rel=\"noopener\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u8ca1\u56e3<\/a><\/strong>\u306e\u30b3\u30db\u30fc\u30c8<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u304a\u3088\u3073\u95a2\u9023\u3059\u308b\u904b\u52d5\u969c\u5bb3\uff08STELLENBOS\uff09\u306e\u907a\u4f1d\u5b66\u7684\u7814\u7a76\u3001\u30b9\u30c6\u30ec\u30f3\u30dc\u30c3\u30b7\u30e5\u5927\u5b66\u306e\u5357\u30a2\u30d5\u30ea\u30ab\u306e\u30b3\u30db\u30fc\u30c8 <\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30de\u30ec\u30fc\u30b7\u30a2\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u907a\u4f1d\u5b66\u30b3\u30db\u30fc\u30c8\uff08UMKLM\uff09\u3001\u30de\u30e9\u30e4\u5927\u5b66\u306e\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u30b3\u30db\u30fc\u30c8<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u304a\u3088\u3073\u95a2\u9023\u904b\u52d5\u969c\u5bb3\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u578b-\u8868\u73fe\u578b\u76f8\u95a2\uff08KUL\uff09\u3001\u30de\u30ec\u30fc\u30b7\u30a2\u5927\u5b66\u306e\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u30b3\u30db\u30fc\u30c8<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u304a\u3088\u3073\u904b\u52d5\u969c\u5bb3\u30bb\u30f3\u30bf\u30fc\u30d0\u30a4\u30aa\u30ea\u30dd\u30b8\u30c8\u30ea\uff08PDMDC\uff09\u3001\u30ce\u30fc\u30b9\u30a6\u30a7\u30b9\u30bf\u30f3\u5927\u5b66\u306e\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u30b3\u30db\u30fc\u30c8<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u8907\u5408\u75be\u60a3GP2\u53c2\u52a0\u8005\u306e\u907a\u4f1d\u7684\u7956\u5148\u306f\u300110\u306e\u7956\u5148\u30b0\u30eb\u30fc\u30d7\uff08\u4ee5\u4e0b\u306e9\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u3068\u5c11\u6570\u306e\u30d5\u30a3\u30f3\u30e9\u30f3\u30c9\u30e8\u30fc\u30ed\u30c3\u30d1\u4eba\uff09\u306b\u5206\u3051\u3089\u308c\u3066\u3044\u307e\u3059\uff1b\u4ee5\u4e0b\u306e\u8868\u306f\u3001\u3053\u306e\u30ea\u30ea\u30fc\u30b9\u306b\u304a\u3051\u308b\u8907\u5408\u75be\u60a3\u53c2\u52a0\u8005\u306e\u907a\u4f1d\u7684\u7956\u5148\u3092\u8a73\u7d30\u306b\u793a\u3057\u3001\u54c1\u8cea\u7ba1\u7406\u306b\u5408\u683c\u3057\u3001\u5e30\u5c5e\u3055\u308c\u305f\u3082\u306e\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u30c7\u30fc\u30bf\u306b\u306f\u3001\u65b0\u3057\u3044\u30af\u30e9\u30b9\u30bf\u30fc\u30d5\u30a1\u30a4\u30eb\u3092\u4f7f\u7528\u3057\u3066\u518d\u30af\u30e9\u30b9\u30bf\u30fc\u5316\u3055\u308c\u3001\u73fe\u5728\u306e\u30ea\u30ea\u30fc\u30b9\u306b\u56fa\u6709\u306e\u65b0\u3057\u304f\u30b8\u30a7\u30ce\u30bf\u30a4\u30d4\u30f3\u30b0\u304a\u3088\u3073\u5171\u6709\u3055\u308c\u305f\u30b5\u30f3\u30d7\u30eb\u3068\u3068\u3082\u306b\u54c1\u8cea\u7ba1\u7406\u3092\u884c\u3063\u305f\u3001\u4ee5\u524d\u306e\u30ea\u30ea\u30fc\u30b9\u30b5\u30f3\u30d7\u30eb\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/span><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-50006385 aligncenter\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1.jpg\" alt=\"\" width=\"800\" height=\"767\" srcset=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1.jpg 1024w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1-300x288.jpg 300w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1-768x737.jpg 768w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1-256x246.jpg 256w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1-512x491.jpg 512w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_ComplexDisease_v1-751x720.jpg 751w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><b>\u672c\u30ea\u30ea\u30fc\u30b9\u306b\u304a\u3051\u308b\u91cd\u8981\u306a\u70b9<\/b><span style=\"font-weight: 400;\">\uff1a<\/span><span style=\"font-weight: 400;\">STELLENBOS<\/span><span style=\"font-weight: 400;\">\u306f\u5357\u30a2\u30d5\u30ea\u30ab\u306e\u30b3\u30db\u30fc\u30c8\u3067\u3001\u5730\u57df\u3068\u305d\u306e\u6b74\u53f2\u3092\u53cd\u6620\u3057\u305f\u907a\u4f1d\u7684\u7956\u5148\u306e\u6df7\u5408\u3092\u8868\u3057\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u306e\u30e1\u30f3\u30d0\u30fc\u306b\u5bfe\u3059\u308b\u7956\u5148\u4e88\u6e2c\u306e\u4e00\u90e8\u306f\u3001\u5c06\u6765\u306e\u30ea\u30ea\u30fc\u30b9\u3067\u65b0\u3057\u3044\u4eba\u53e3\u7fa4\u306e\u8abf\u6574\u306b\u3088\u3063\u3066\u5909\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u672c\u30ea\u30ea\u30fc\u30b9\u3067\u306f\u3001\u7814\u7a76\u8005\u304cTier 2\u30c7\u30fc\u30bf\u306e\u4e00\u90e8\u3068\u3057\u3066\u5206\u6790\u306b\u9ad8\u6df7\u548c\u6027\u3092\u542b\u3081\u308b\u304b\u3069\u3046\u304b\u3001\u305d\u306e\u65b9\u6cd5\u3092\u9078\u629e\u3067\u304d\u308b\u3088\u3046\u306b\u3001\u3059\u3079\u3066\u306e\u53c2\u52a0\u8005\u306b\u6df7\u548c\u6027\u63a8\u5b9a\u5024\u3092\u63d0\u4f9b\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u6df7\u548c\u6027\u304c\u9ad8\u3044\u3068\u73fe\u5728\u306e\u30e2\u30c7\u30eb\u304b\u3089\u306e\u7956\u5148\u4e88\u6e2c\u306e\u4fe1\u983c\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u305f\u3081\u3001\u3053\u306e\u6bb5\u968e\u3067\u5206\u6790\u304b\u3089\u524a\u9664\u3059\u308b\u3053\u3068\u3092\u63a8\u5968\u3059\u308b\u30b5\u30f3\u30d7\u30eb\u306e\u30ea\u30b9\u30c8\u3082\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3GP2\u53c2\u52a0\u8005\u306e\u907a\u4f1d\u7684\u306b\u540c\u5b9a\u3055\u308c\u305f\u7956\u5148\u306f\u3001\u8907\u5408\u53c2\u52a0\u8005\u3068\u540c\u3058\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\u304b\u3089\u63a8\u5b9a\u3055\u308c\u307e\u3059\u3002\u4ee5\u4e0b\u306e\u8868\u306f\u3001GP2\u30ea\u30ea\u30fc\u30b95\u306b\u304a\u3051\u308b\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3\u53c2\u52a0\u8005\u306e\u907a\u4f1d\u7684\u306b\u540c\u5b9a\u3055\u308c\u305f\u7956\u5148\u3092\u8a73\u8ff0\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-50006434 aligncenter\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1.jpg\" alt=\"\" width=\"800\" height=\"477\" srcset=\"https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1.jpg 1024w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1-300x179.jpg 300w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1-768x458.jpg 768w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1-256x153.jpg 256w, https:\/\/gp2.org\/wp-content\/uploads\/2023\/05\/102049-010_GP2Blogs_DataChart_Release5_2_MonogenicDisease_v1r1-512x305.jpg 512w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u4eca\u5f8c\u306e\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u306b\u3088\u308a\u3001\u53c2\u52a0\u8005\u306e\u591a\u69d8\u6027\u304c\u5897\u3057\u307e\u3059\u3002\u3092\u30c1\u30a7\u30c3\u30af\u3057\u3066\u9032\u6357\u72b6\u6cc1\u3092\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002<\/span><span style=\"font-weight: 400;\">\u672c\u30ea\u30ea\u30fc\u30b9\u306e\u91cd\u8981\u306a\u66f4\u65b0\u306f\u3001\u3069\u306e\u53c2\u52a0\u8005\u304c\u8840\u7e01\u95a2\u4fc2\u304c\u3042\u308b\u304b\u3092\u5224\u65ad\u3059\u308b\u65b9\u6cd5\u306b\u5c0f\u3055\u306a\u5909\u66f4\u304c\u52a0\u3048\u3089\u308c\u305f\u3053\u3068\u3067\u3059\u3002\u79c1\u305f\u3061\u306f\u73fe\u5728\u3001<strong><a href=\"https:\/\/www.kingrelatedness.com\/\" target=\"_blank\" rel=\"noopener\">KING\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2<\/a><\/strong><\/span><span style=\"font-weight: 400;\">\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u5909\u66f4\u306b\u3088\u308a\u3001\u4ee5\u524d\u306b\u30ea\u30ea\u30fc\u30b9\u3055\u308c\u305f\u53c2\u52a0\u8005\u306e\u4e00\u90e8\u306e\u95a2\u4fc2\u6027\u63a8\u5b9a\u5024\u304c\u66f4\u65b0\u3055\u308c\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u5909\u66f4\u306b\u3088\u308a\u3001\u63a8\u5b9a\u95a2\u9023\u6027\u306e\u95be\u5024\u3092\u8a73\u8ff0\u3057\u305f\u30d5\u30a1\u30a4\u30eb\u304c\u30ea\u30ea\u30fc\u30b9\u3067\u5229\u7528\u53ef\u80fd\u306b\u306a\u308a\u3001\u7814\u7a76\u8005\u306f\u72ec\u81ea\u306e\u30ab\u30b9\u30bf\u30e0\u30d5\u30a3\u30eb\u30bf\u30ea\u30f3\u30b0\u306e\u76ee\u7684\u3067\u4f7f\u7528\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u4e88\u6e2c\u3055\u308c\u308b\u4e3b\u8981\u7d20\u306b\u52a0\u3048\u3001\u4e0b\u6d41\u306e\u5206\u6790\u306b\u5229\u7528\u53ef\u80fd\u306a\u7956\u5148\u3054\u3068\u306b\u8a08\u7b97\u3055\u308c\u305f\u4e3b\u8981\u7d20\u304c\u542b\u307e\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u00a0<\/span><\/p>\n<p><b>\u7d71\u8a08\u307e\u3068\u3081\uff1a<\/b><\/p>\n<p><span style=\"font-weight: 400;\">\u672c\u30ea\u30ea\u30fc\u30b9\u3067\u306f\u3001\u65b0\u3057\u3044\u7d71\u8a08\u307e\u3068\u3081\u3082\u30c6\u30a3\u30a21\u30a2\u30af\u30bb\u30b9\u3092\u901a\u3058\u3066\u5229\u7528\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002Kim et al 2023\u3082\u3001<a href=\"https:\/\/ndkp.hugeamp.org\/\" target=\"_blank\" rel=\"noopener\"><strong>\u795e\u7d4c\u5909\u6027\u75be\u60a3\u77e5\u8b58\u30dd\u30fc\u30bf\u30eb<\/strong><\/a><\/span>\u3068\u306e\u7d99\u7d9a\u7684\u306a\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\u3092\u901a\u3058\u3066\u5229\u7528\u3067\u304d\u307e\u3059\u3002<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8422160\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"><strong>Nalls et al 2019<\/strong><\/span><\/a><span style=\"font-weight: 400;\">\u300023andme in hg38\u3092\u9664\u304f\uff08\u6b27\u5dde\u6700\u5927\u306ePD GWAS\uff09<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/ana.26153\" target=\"_blank\" rel=\"noopener\">Loesch et al 2021<\/a><\/strong><span style=\"font-weight: 400;\">\uff08\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u30fb\u30a2\u30e1\u30ea\u30ab\u30f3\u30a4\u30f3\u30c7\u30a3\u30a2\u30f3\u6700\u5927\u306ePD GWAS\uff09<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.08.04.22278432v1\" target=\"_blank\" rel=\"noopener\">Kim et al 202<\/a><\/strong><span style=\"font-weight: 400;\">\u300023andme\u3092\u9664\u304f\uff08\u30e8\u30fc\u30ed\u30c3\u30d1\u3001\u6771\u30a2\u30b8\u30a2\u3001\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u30fb\u30a2\u30e1\u30ea\u30ab\u30f3\u30a4\u30f3\u30c7\u30a3\u30a2\u30f3\u3001\u30a2\u30d5\u30ea\u30ab\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u3092\u542b\u3080PD\u30ea\u30b9\u30af\u306e\u591a\u7956\u5148\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff09<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2023.05.05.23289529v1\" target=\"_blank\" rel=\"noopener\">Rizig et al 2023<\/a><\/strong> 23andme in hg38\u3092\u9664\u304f\uff08\u30a2\u30d5\u30ea\u30ab\u3068\u30a2\u30d5\u30ea\u30ab\u6df7\u5408\u6700\u5927\u306ePD GWAS\uff1bGP2\u30ea\u30ea\u30fc\u30b95\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\uff09<\/li>\n<\/ul>\n<p><b>\u30b3\u30d4\u30fc\u756a\u53f7\u30d0\u30ea\u30a2\u30f3\u30c8\uff1a<\/b><\/p>\n<p><span style=\"font-weight: 400;\">\u54c1\u8cea\u7ba1\u7406\u306b\u5408\u683c\u3057\u305f\u3059\u3079\u3066\u306e\u907a\u4f1d\u5b50\u578b\u30b5\u30f3\u30d7\u30eb\uff08\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3068250kb\u306e\u96a3\u63a5\u9818\u57df\uff09\u306e\u30b3\u30d4\u30fc\u756a\u53f7\u30d0\u30ea\u30a2\u30f3\u30c8\uff08CNV\uff09\u30b3\u30fc\u30eb\u306f\u3001\u30ea\u30ea\u30fc\u30b95\u306e\u5168\u30b5\u30f3\u30d7\u30eb\u3092\u542b\u3080\u3088\u3046\u306b\u66f4\u65b0\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u30c7\u30fc\u30bf\u306f\u3001\u30ab\u30b9\u30bf\u30e0GP2\u907a\u4f1d\u5b50\u578b\u30af\u30e9\u30b9\u30bf\u30ea\u30f3\u30b0\u30d5\u30a1\u30a4\u30eb\uff08Tier 1 \u3068 Tier 2 \u306e\u4e21\u65b9\u306e\u30c7\u30fc\u30bf \u30a2\u30af\u30bb\u30b9\u306e\u4e0b\u306b\u3042\u308b <\/span><b>utils<\/b><span style=\"font-weight: 400;\"> \u30c7\u30a3\u30ec\u30af\u30c8\u30ea\u3067\u5229\u7528\u53ef\u80fd\uff09\u3092\u4f7f\u7528\u3057\u3066\u30af\u30e9\u30b9\u30bf\u30fc\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u78ba\u7387\u7684CNV\u30b3\u30fc\u30eb\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306b\u4f7f\u7528\u3055\u308c\u308b\u30af\u30e9\u30b9\u30bf\u30fc\u30d5\u30a1\u30a4\u30eb\u3068\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\u306f\u3001\u3069\u3061\u3089\u3082GP2\u5916\u306e\u30c7\u30fc\u30bf\u3067\u4f7f\u7528\u3059\u308b\u305f\u3081<strong><a href=\"https:\/\/github.com\/GP2code\" target=\"_blank\" rel=\"noopener\">GP2 Github<\/a><\/strong><\/span><span style=\"font-weight: 400;\">\u306b\u3042\u308a\u307e\u3059\u3002\u30ab\u30b9\u30bf\u30e0GP2\u30b8\u30a7\u30ce\u30bf\u30a4\u30d4\u30f3\u30b0\u30af\u30e9\u30b9\u30bf\u30ea\u30f3\u30b0\u30d5\u30a1\u30a4\u30eb\u3092\u4f7f\u3063\u305f\u30af\u30e9\u30b9\u30bf\u30ea\u30f3\u30b0\u3068\u30b3\u30d4\u30fc\u756a\u53f7\u30d0\u30ea\u30a2\u30f3\u30c8\u78ba\u7387\u30b3\u30fc\u30eb\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001GP2\u30d6\u30ed\u30b0\u306e<\/span><strong><a href=\"https:\/\/gp2.org\/the-components-of-gp2s-third-data-release\/#:~:text=In%20October%202022%2C%20GP2%20announced,samples%20as%20the%20previous%20release.\" target=\"_blank\" rel=\"noopener\">\u300cGP2\u306e\u7b2c3\u6b21\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u306e\u30b3\u30f3\u30dd\u30fc\u30cd\u30f3\u30c8\u300d<\/a><\/strong>\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<span style=\"font-weight: 400;\">\u8907\u5408\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u578b\u3068\u81e8\u5e8a\u30c7\u30fc\u30bf\u306e\u69cb\u9020\u306b\u95a2\u3059\u308b\u3088\u308a\u8a73\u7d30\u306a\u60c5\u5831\u306f\u3001\u3053\u306e\u30ea\u30ea\u30fc\u30b9\u3067\u66f4\u65b0\u3055\u308c\u3001\u516c\u5f0fGP2\u30c6\u30e9\u30ef\u30fc\u30af\u30b9\u30da\u30fc\u30b9\u3067\u5165\u624b\u53ef\u80fd\u306aREADME\u3068\u540c\u69d8\u3001<\/span><span style=\"font-weight: 400;\">\u30d6\u30ed\u30b0\u8a18\u4e8b\u3067\u8a73\u8ff0\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30afPD WGS\u30c7\u30fc\u30bf\u3082\u540c\u3058README\u306b\u8a73\u8ff0\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u00a0<\/span><\/p>\n<p><b>\u3053\u308c\u307e\u3067\u901a\u308a\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\u3001\u30c7\u30fc\u30bf\u3001\u304a\u3088\u3073\u5206\u6790\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001\u5404GP2\u30ea\u30ea\u30fc\u30b9\u306b\u4ed8\u5c5e\u306eREADME\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/b><\/p>\n<hr \/>\n<p><em><span style=\"font-weight: 400;\">GP2\u8907\u5408\u75be\u60a3\u30c7\u30fc\u30bf\u89e3\u6790\u3001\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u30c7\u30fc\u30bf\u89e3\u6790\u3001\u30c7\u30fc\u30bf\u30fb\u30b3\u30fc\u30c9\u5c55\u958b\u30ef\u30fc\u30ad\u30f3\u30b0\u30b0\u30eb\u30fc\u30d7\u4ee3\u8868<\/span><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3053\u306e\u30ea\u30ea\u30fc\u30b9\u306b\u306f\u3001\u65b0\u305f\u306b7462\u4eba\u306e\u8907\u5408\u75be\u60a3\u306e\u53c2\u52a0\u8005\u304a\u3088\u3073487\u4eba\u306e\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3\u306e\u53c2\u52a0\u8005\u304c\u8ffd\u52a0\u3055\u308c\u3001\u8907\u5408\u30fb\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304b\u3089\u306e\u3053\u308c\u307e\u3067\u306e\u30ea\u30ea\u30fc\u30b9\u306b\u8ffd\u52a0\u3055\u308c\u307e\u3057\u305f\u3002\u00a0<\/p>\n","protected":false},"author":0,"featured_media":50024715,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50012017","post","type-post","status-publish","format-standard","hentry","post-type-741","post-type-722","post-type-720","topic-research-operations-3"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50012017","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/comments?post=50012017"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50012017\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media\/50024715"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media?parent=50012017"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}