{"id":50011915,"date":"2022-01-10T07:57:06","date_gmt":"2022-01-10T12:57:06","guid":{"rendered":"https:\/\/gp2stg.wpenginepowered.com\/gp2%e3%81%ae%e5%88%9d%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9\/"},"modified":"2024-10-21T15:13:02","modified_gmt":"2024-10-21T19:13:02","slug":"gp2%e3%81%ae%e5%88%9d%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9","status":"publish","type":"post","link":"https:\/\/gp2.org\/ja\/gp2%e3%81%ae%e5%88%9d%e3%83%87%e3%83%bc%e3%82%bf%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%81%ae%e5%86%85%e5%ae%b9\/","title":{"rendered":"GP2\u306e\u521d\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u306e\u5185\u5bb9"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">2021\u5e7412\u6708\u3001GP2\u306f<\/span><a href=\"https:\/\/amp-pd.org\/register-for-amp-pd\" target=\"_blank\" rel=\"noopener\"><strong>AMP\u00ae<\/strong><span style=\"font-weight: 400;\"><strong> PD\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0<\/strong><\/span><\/a><span style=\"font-weight: 400;\">\u3067\u521d\u306eGP2\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u30ea\u30ea\u30fc\u30b9\u3067\u5229\u7528\u53ef\u80fd\u306b\u306a\u308b\u30c7\u30fc\u30bf\u306f\u3001CORIELL\u3001\u30d9\u30a4\u30e9\u30fc\u533b\u79d1\u5927\u5b66\uff08BCM\uff09\u3001BCM-\u30e1\u30ea\u30fc\u30e9\u30f3\u30c9\u5927\u5b66\uff08UMD\uff09\u306e\u30b3\u30db\u30fc\u30c8\u304b\u30894,908\u4eba\u306e\u53c2\u52a0\u8005\uff083,434 PD\u30011,474\u975ePD\uff09\u306b\u3088\u3063\u3066\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u7684\u306b\u6c7a\u5b9a\u3055\u308c\u305fGP2\u53c2\u52a0\u8005\u306e\u7956\u5148\u306f\u30018\u3064\u306e\u7956\u5148\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002\u4ee5\u4e0b\u306e\u8868\u306fGP2\u30ea\u30ea\u30fc\u30b91\u306e\u53c2\u52a0\u8005\u306e\u907a\u4f1d\u7684\u306b\u6c7a\u5b9a\u3055\u308c\u305f\u7956\u5148\u306e\u5185\u8a33\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-21437 aligncenter\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2021\/12\/ancestry-table-1024x641.jpg\" alt=\"\" width=\"600\" height=\"376\" \/><span style=\"font-weight: 400;\">\u4eca\u5f8c\u306e\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u3067\u3001\u5229\u7528\u53ef\u80fd\u306a\u53c2\u52a0\u8005\u306e\u591a\u69d8\u6027\u3092\u3055\u3089\u306b\u62e1\u5927\u3057\u307e\u3059\u3002<\/span><a href=\"https:\/\/gp2.org\/cohort-dashboard\/\" rel=\"\"><span style=\"font-weight: 400;\"><strong>\u30c0\u30c3\u30b7\u30e5\u30dc\u30fc\u30c9<\/strong><\/span><\/a><span style=\"font-weight: 400;\">\u3067\u9032\u6357\u72b6\u6cc1\u3092\u78ba\u8a8d\u3057\u3066\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/span><\/p>\n<h3>\u907a\u4f1d\u5b50\u578b\u30c7\u30fc\u30bf<\/h3>\n<p><span style=\"font-weight: 400;\">\u3059\u3079\u3066\u306e\u30c7\u30fc\u30bf\u306e\u907a\u4f1d\u5b50\u578b\u306f\u30a4\u30eb\u30df\u30ca\u30fb\u30cb\u30e5\u30fc\u30ed\u30d6\u30fc\u30b9\u30bf\u30fc\u30a2\u30ec\u30a4\u3067\u7279\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u30a2\u30ec\u30a4\u306f\u591a\u69d8\u306a\u4eba\u53e3\u96c6\u56e3\u306e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u5909\u7570\u7528\u306b\u7279\u5225\u306b\u8a2d\u8a08\u3055\u308c\u307e\u3057\u305f\u3002\u30c7\u30fc\u30bf\u306f\u6a19\u6e96\u30a4\u30eb\u30df\u30ca\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u57fa\u3065\u3044\u3066\u51e6\u7406\u3055\u308c\u3001\u54c1\u8cea\u7ba1\u7406\u306f\u30aa\u30fc\u30d7\u30f3\u30bd\u30fc\u30b9\u306eQC\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\u3092\u4f7f\u3063\u3066GP2\u304c\u884c\u3044\u307e\u3059\u3002\u305d\u306e\u5f8c\u30c7\u30fc\u30bf\u306f\u500b\u5225\u306e\u7956\u5148\u30b0\u30eb\u30fc\u30d7\u5185\u3067TOPMed\u3092\u4f7f\u3063\u3066\u5165\u529b\u3055\u308c\u307e\u3059\u3002\u65e2\u77e5\u306e\u91cd\u8907\u306f\u3059\u3079\u3066\u524a\u9664\u3055\u308c\u307e\u3059\u304c\u3001\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u5206\u6790\u306e\u67d4\u8edf\u6027\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u95a2\u9023\u30b5\u30f3\u30d7\u30eb\u306f\u6b8b\u3057\u307e\u3059\u3002<\/span><span style=\"font-weight: 400;\">QC\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\u306b\u542b\u307e\u308c\u308b\u3082\u306e\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001\u95a2\u9023\u306e<strong><a href=\"https:\/\/github.com\/GP2code\/GenoTools\" target=\"_blank\" rel=\"noopener\">GitHub\u30da\u30fc\u30b8<\/a><\/strong>\u3067\u8a73\u8aac\u306e\u30ef\u30fc\u30af\u30d5\u30ed\u30fc\u3092\u304a\u8aad\u307f\u304f\u3060\u3055\u3044\u3002<\/span><\/p>\n<h3>\u81e8\u5e8a\u30c7\u30fc\u30bf<\/h3>\n<p><span style=\"font-weight: 400;\">\u81e8\u5e8a\u30c7\u30fc\u30bf\u3092\u53d6\u308a\u5165\u308c\u3001\u7d71\u4e00\u3055\u308c\u305fGP2\u81e8\u5e8a\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u3092\u69cb\u7bc9\u3057\u307e\u3057\u305f\u3002\u81e8\u5e8a\u30c7\u30fc\u30bf\u306e\u6700\u4f4e\u8981\u4ef6\u306b\u306f\u4eba\u53e3\u7d71\u8a08\u3001\u63a1\u7528\u30ab\u30c6\u30b4\u30ea\u30fc\u3001\u5bb6\u65cf\u6b74\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/span><span style=\"font-weight: 400;\">GP2\u30b3\u30a2\u30c7\u30fc\u30bf\u8981\u4ef6\u30ec\u30d9\u30eb\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001<span style=\"font-weight: 400;\"><strong><a title=\"\u30ea\u30bd\u30fc\u30b9\" href=\"\/resources\/\" rel=\"\">\u3000\u30ea\u30bd\u30fc\u30b9\u30bb\u30af\u30b7\u30e7\u30f3\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8<\/a><\/strong>\u306b\u3042\u308b<\/span><span style=\"font-weight: 400;\">\u300c<a href=\"https:\/\/gp2.org\/wp-content\/uploads\/sites\/2\/2020\/10\/GP2_Cohort_clinical-data-core-data-set_table_October2020-1.pdf\" target=\"_blank\" rel=\"noopener\">\u81e8\u5e8a\u30c7\u30fc\u30bf\u3000\u30b3\u30a2\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8<\/a>\u300d\u306e\u8cc7\u6599<\/span>\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><span style=\"font-weight: 400;\">\u30c7\u30fc\u30bf\u306f<strong><a href=\"https:\/\/app.terra.bio\/#\" target=\"_blank\" rel=\"noopener\">Terra\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0<\/a><\/strong>\u304b\u3089\u30a2\u30af\u30bb\u30b9\u3067\u304d\u307e\u3059\u3002\u00a0<\/span><span style=\"font-weight: 400;\">GP2\u30c7\u30fc\u30bf\u306b\u30a2\u30af\u30bb\u30b9\u3059\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u306f\u3001\u30d6\u30ed\u30b0\u300c<\/span><strong><a href=\"https:\/\/gp2.org\/applying-for-gp2-data-access-on-the-amp-pd-platform\/\" rel=\"\">AMP\u00ae PD\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306eGP2\u30c7\u30fc\u30bf\u30a2\u30af\u30bb\u30b9\u306e\u7533\u8acb\u306b\u3064\u3044\u3066<\/a><\/strong><span style=\"font-weight: 400;\">\u300d\u3092\u304a\u8aad\u307f\u304f\u3060\u3055\u3044\u3002\u6b21\u306e\u30c7\u30fc\u30bf\u88fd\u54c1\u306fGP2\u30ea\u30ea\u30fc\u30b91\u306eTerra\u3067\u5229\u7528\u53ef\u80fd\u3067\u3059\uff1a<\/span><\/p>\n<ul>\n<li><b>Tier 1 \u30c7\u30fc\u30bf\u30a2\u30af\u30bb\u30b9<\/b><b><\/b>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u6700\u65b0\u306e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5GWAS\uff08<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31701892\/\" target=\"_blank\" rel=\"noopener\">Nalls et al. 2019<\/a><\/strong>\u306e23andMe\u30b5\u30f3\u30d7\u30eb\u3092\u9664\u304f\uff09\u304b\u3089\u306e\u8981\u7d04\u7d71\u8a08<\/span><\/li>\n<\/ul>\n<\/li>\n<li><b>Tier 2 \u30c7\u30fc\u30bf\u30a2\u30af\u30bb\u30b9<\/b><b><\/b>\n<ul>\n<li><span style=\"font-weight: 400;\"><em>\u672a\u51e6\u7406\u306e\u907a\u4f1d\u5b50\u578b\uff1a<\/em>\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u524d\u306b\u54c1\u8cea\u7ba1\u7406\u306b\u5408\u683c\u3057\u305f\u3059\u3079\u3066\u306e\u30b5\u30f3\u30d7\u30eb\u306e\u5404\u7956\u5148\u30b0\u30eb\u30fc\u30d7\u306ePLINK2 .pgen\u30d5\u30a1\u30a4\u30eb<\/span><\/li>\n<li><em><span style=\"font-weight: 400;\">\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u907a\u4f1d\u5b50\u578b\uff1a<\/span><\/em><span style=\"font-weight: 400;\">TOPMed\u53c2\u7167\u30d1\u30cd\u30eb\u3092\u4f7f\u3063\u3066\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u3057\u305fPLINK2.pgen\u30d5\u30a1\u30a4\u30eb\uff08\u30c7\u30fc\u30bf\u30ea\u30ea\u30fc\u30b9\u306b\u4ed8\u968f\u3059\u308breadme\u30d5\u30a1\u30a4\u30eb\u306b\u8a73\u8ff0\u3055\u308c\u3066\u3044\u308b\u6700\u4f4eQC\u30d5\u30a3\u30eb\u30bf\u30ea\u30f3\u30b0\u306b\u5408\u683c\uff09<\/span><\/li>\n<li><span style=\"font-weight: 400;\"><em>\u30e1\u30bf\u30c7\u30fc\u30bf\uff1a<\/em>QC\u51fa\u529b\u3068\u7956\u5148\u4e88\u6e2c\u306b\u95a2\u3059\u308b\u60c5\u5831\u3092\u542b\u3080<\/span><\/li>\n<li><em><span style=\"font-weight: 400;\">\u81e8\u5e8a\u30c7\u30fc\u30bf\uff1a<\/span><\/em><span style=\"font-weight: 400;\">\u81e8\u5e8a\u30c7\u30fc\u30bf\u30d5\u30a3\u30fc\u30eb\u30c9\u304a\u3088\u3073\u95a2\u9023\u81e8\u5e8a\u30c7\u30fc\u30bf\u8f9e\u66f8<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u3053\u306e\u79c1\u305f\u3061\u306f\u3053\u308c\u304c\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u7814\u7a76\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306b\u3068\u3063\u3066\u8cb4\u91cd\u306a\u30ea\u30bd\u30fc\u30b9\u306b\u306a\u308b\u3053\u3068\u3092\u9858\u3063\u3066\u3044\u307e\u3059\u3002\u7d99\u7d9a\u7684\u306a\u30d7\u30ed\u30bb\u30b9\u306e\u6539\u5584\u3092\u901a\u3057\u3066\u3001\u4eca\u5f8c\u306e\u3055\u3089\u306a\u308b\u9032\u5c55\u306b\u3054\u671f\u5f85\u4e0b\u3055\u3044\u3002<\/span><img loading=\"lazy\" decoding=\"async\" class=\"size-large wp-image-50009864 aligncenter\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-1024x621.png\" alt=\"\" width=\"1024\" height=\"621\" srcset=\"https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-1024x621.png 1024w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-300x182.png 300w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-768x466.png 768w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-256x155.png 256w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-512x310.png 512w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs-1188x720.png 1188w, https:\/\/gp2.org\/wp-content\/uploads\/2022\/01\/GP2_round1_projected_pcs.png 1275w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\u3053\u306e\u30d6\u30ed\u30b0\u306fHampton Leonard\u3001Mike Nalls\u3001Yeajin Song\u3001Dan Vitale\u304c\u5171\u540c\u3067\u57f7\u7b46\u3057\u307e\u3057\u305f\u3002\u57f7\u7b46\u8005\u306e\u7d4c\u6b74\u306b\u3064\u3044\u3066\u306f\u3001GP2<strong><a href=\"\/working-groups\/complex-disease-data-analysis-working-group\/\" rel=\"\">\u8907\u5408\u75be\u60a3\u3000\u30c7\u30fc\u30bf\u5206\u6790\u30ef\u30fc\u30ad\u30f3\u30b0\u30b0\u30eb\u30fc\u30d7<\/a><\/strong>\u306e\u30da\u30fc\u30b8\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u907a\u4f1d\u5b50\u578b\u3084\u81e8\u5e8a\u30c7\u30fc\u30bf\u3092\u53ce\u96c6\u3059\u308b\u30d7\u30ed\u30bb\u30b9\u3001\u5229\u7528\u53ef\u80fd\u306a\u30c7\u30fc\u30bf\u30a2\u30af\u30bb\u30b9\u306eTier \u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u77e5\u308b\u3002<\/p>\n","protected":false},"author":0,"featured_media":50024765,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50011915","post","type-post","status-publish","format-standard","hentry","post-type-741","post-type-722","post-type-720","topic-research-operations-3"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50011915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/comments?post=50011915"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50011915\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media\/50024765"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media?parent=50011915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}