{"id":50011815,"date":"2020-09-27T08:40:11","date_gmt":"2020-09-27T12:40:11","guid":{"rendered":"https:\/\/gp2-stage-updated.local\/%e3%81%aa%e3%81%9c%e7%95%b0%e3%81%aa%e3%82%8b%e4%ba%ba%e5%8f%a3%e9%9b%86%e5%9b%a3%e3%81%a7%e7%97%85%e6%b0%97%e3%82%92%e7%a0%94%e7%a9%b6%e3%81%99%e3%82%8b%e3%81%ae%e3%81%a7%e3%81%99%e3%81%8b%ef%bc%9f\/"},"modified":"2024-10-21T14:59:58","modified_gmt":"2024-10-21T18:59:58","slug":"%e3%81%aa%e3%81%9c%e7%95%b0%e3%81%aa%e3%82%8b%e4%ba%ba%e5%8f%a3%e9%9b%86%e5%9b%a3%e3%81%a7%e7%97%85%e6%b0%97%e3%82%92%e7%a0%94%e7%a9%b6%e3%81%99%e3%82%8b%e3%81%ae%e3%81%a7%e3%81%99%e3%81%8b%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/gp2.org\/ja\/%e3%81%aa%e3%81%9c%e7%95%b0%e3%81%aa%e3%82%8b%e4%ba%ba%e5%8f%a3%e9%9b%86%e5%9b%a3%e3%81%a7%e7%97%85%e6%b0%97%e3%82%92%e7%a0%94%e7%a9%b6%e3%81%99%e3%82%8b%e3%81%ae%e3%81%a7%e3%81%99%e3%81%8b%ef%bc%9f\/","title":{"rendered":"\u306a\u305c\u7570\u306a\u308b\u4eba\u53e3\u96c6\u56e3\u3067\u75c5\u6c17\u3092\u7814\u7a76\u3059\u308b\u306e\u3067\u3059\u304b\uff1f"},"content":{"rendered":"<p>\u30b9\u30da\u30a4\u30f3\u3067\u80b2\u3061\u3001\u79d1\u5b66\u8005\u3068\u3057\u3066\u306e\u30ad\u30e3\u30ea\u30a2\u3092\u59cb\u3081\u307e\u3057\u305f\u304c\u3001\u6700\u521d\u306e\u30d2\u30c8\u30b2\u30ce\u30e0\u304c\u914d\u5217\u6c7a\u5b9a\u3055\u308c\u308b\u524d\u306b\u3001\u7814\u7a76\u304c\u6975\u7aef\u306b\u30e8\u30fc\u30ed\u30c3\u30d1\u4e2d\u5fc3\u7684\u3067\u3042\u308b\uff08\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u306e\u4eba\u53e3\u96c6\u56e3\u306e\u307f\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u308b\uff09\u3053\u3068\u306f\u5168\u304f\u8003\u3048\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30e9\u30c6\u30f3\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u304c\u5927\u90e8\u5206\u3092\u5360\u3081\u308b\u30d5\u30ed\u30ea\u30c0\u5dde\u306b2004\u5e74\u306b\u5f15\u3063\u8d8a\u3057\u3001\u4e3b\u306b\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u306e\u53c2\u52a0\u8005\u304b\u3089\u306e\u30b5\u30f3\u30d7\u30eb\u306e\u307f\u3092\u53d6\u308a\u6271\u3063\u3066\u3044\u305f\u6642\u3067\u3082\u3001\u305d\u306e\u80cc\u5f8c\u306b\u3042\u308b\u7406\u7531\u3092\u8003\u3048\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<p><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;\u3057\u304b\u3057\u30012006\u5e74\u306b\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u904b\u52d5\u969c\u5bb3\u5354\u4f1a\u304c\u4e3b\u50ac\u3057\u305f\u30da\u30eb\u30fc\u3067\u306e\u4f1a\u8b70\u3067\u8b1b\u6f14\u3092\u3057\u305f\u306e\u3067\u3059\u304c\u3001\u6ede\u5728\u4e2d\u306b\u3053\u306e\u5206\u91ce\u306b\u304a\u3051\u308b\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u4eba\u7814\u7a76\u5bfe\u8c61\u306e\u5c11\u306a\u3055\u306b\u9a5a\u304d\u307e\u3057\u305f\u3002&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:4993,&quot;3&quot;:{&quot;1&quot;:0},&quot;10&quot;:1,&quot;11&quot;:4,&quot;12&quot;:0,&quot;15&quot;:&quot;Arial&quot;}\">\u3057\u304b\u3057\u30012006\u5e74\u306b\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u904b\u52d5\u969c\u5bb3\u5354\u4f1a\u304c\u4e3b\u50ac\u3057\u305f\u30da\u30eb\u30fc\u3067\u306e\u4f1a\u8b70\u3067\u8b1b\u6f14\u3092\u3057\u305f\u306e\u3067\u3059\u304c\u3001\u6ede\u5728\u4e2d\u306b\u3053\u306e\u5206\u91ce\u306b\u304a\u3051\u308b\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u4eba\u7814\u7a76\u5bfe\u8c61\u306e\u5c11\u306a\u3055\u306b\u9a5a\u304d\u307e\u3057\u305f<\/span>\u3002\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u306e\u307b\u307c\u3059\u3079\u3066\u306e\u56fd\u306e\u904b\u52d5\u969c\u5bb3\u5c02\u9580\u5bb6\u304c\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\uff08PD\uff09\u907a\u4f1d\u5b66\u306b\u95a2\u3059\u308b\u79c1\u306e\u8a71\u3092\u805e\u3044\u3066\u304f\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u306f<em>LRRK2<\/em>\u3068\u547c\u3070\u308c1\u301c2\uff05\u306e\u78ba\u7387\u3067\u60a3\u8005\u306bPD\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u601d\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u8cea\u7591\u5fdc\u7b54\u4e2d\u306b\u591a\u304f\u306e\u81e8\u5e8a\u533b\u304c\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7a81\u7136\u5909\u7570\u304c\u30e9\u30c6\u30f3\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u306b\u3069\u308c\u307b\u3069\u983b\u7e41\u3067\u3042\u308b\u304b\u3001\u305d\u3057\u3066\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u3059\u3079\u3066\u306e\u60a3\u8005\u3092\u691c\u67fb\u3067\u304d\u308b\u304b\u3092\u77e5\u3063\u3066\u3044\u308b\u304b\u3068\u79c1\u306b\u5c0b\u306d\u307e\u3057\u305f\u3002\u5f7c\u3089\u5168\u54e1\u306e\u524d\u3067\u3001\u79c1\u306f\u305d\u308c\u306b\u3064\u3044\u3066\u306f\u77e5\u3089\u306a\u3044\u3053\u3068\u3092\u8a8d\u3081\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3059\u3079\u3066\u306e\u7814\u7a76\u306f\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u7956\u5148\u3092\u6301\u3064\u4eba\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u30e9\u30c6\u30f3\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u306b\u306f\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u7956\u5148\u3092\u6301\u3064\u4eba\u3082\u3044\u307e\u3059\u304c\u3001\u540c\u3058\u56fd\u5185\u3067\u3042\u3063\u3066\u3082\u3001\u5927\u304d\u306a\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002\u6570\u5e74\u5f8c\u3001\u540c\u3058\u81e8\u5e8a\u533b\u306e\u60a3\u8005\u3067\u884c\u308f\u308c\u305f\u7814\u7a76\u3067\u306f\u3001<em>LRRK2<\/em>\u306e\u7a81\u7136\u5909\u7570\u306e\u983b\u5ea6\u304c\u5e73\u5747\u306e\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u7956\u5148\u306e\u5272\u5408\u306b\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u30da\u30eb\u30fc\u306e\u3088\u3046\u306b\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u907a\u4f1d\u5b50\u304c\u5c11\u306a\u3044\u5834\u5408\u3001\u983b\u5ea6\u3082\u6700\u5c11\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20662 size-full\" src=\"https:\/\/gp2.org\/wp-content\/uploads\/2021\/11\/why-study-disease-graph-image_ja.jpg\" alt=\"\" width=\"590\" height=\"348\" \/><\/p>\n<p>&nbsp;<\/p>\n<p class=\"lede-text\"><em>\u5404\u56fd\u306eLRRK2\u7a81\u7136\u5909\u7570\u306e\u983b\u5ea6\u3068\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u7956\u5148\u306e\u5272\u5408\u306e\u95a2\u4fc2\u3092\u793a\u3059\u30b0\u30e9\u30d5\uff08Zabetian et al. 2017\u3088\u308a\u5f15\u7528)<\/em><\/p>\n<p>\u5225\u306ePD\u907a\u4f1d\u5b50\u3001<em>GBA<\/em>\u306e\u7814\u7a76\u3067\u306f\u3001\u983b\u5ea6\u3060\u3051\u3067\u306a\u304f\u3001\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u5404\u56fd\u3067\u898b\u3089\u308c\u308b\u7a81\u7136\u5909\u7570\u306e\u7a2e\u985e\u3082\u7570\u306a\u308a\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u4eba\u53e3\u96c6\u56e3\u56fa\u6709\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 \u3002<\/p>\n<p>\u3053\u308c\u3089\u306e\u8abf\u67fb\u7d50\u679c\u306f\u3059\u3079\u3066\u3001\u7279\u5b9a\u306e\u6bcd\u96c6\u56e3\u3067\u30c6\u30b9\u30c8\u3059\u308b\u907a\u4f1d\u5b50\u3092\u6c7a\u5b9a\u3059\u308b\u5834\u5408\u3084\u3001\u5404\u60a3\u8005\u30b3\u30db\u30fc\u30c8\u3067\u6700\u3082\u91cd\u8981\u306a\u6cbb\u7642\u6a19\u7684\u3092\u9078\u629e\u3059\u308b\u3068\u304d\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002PD\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b66\u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u77e5\u308b\u3046\u3048\u3067\u3001\u3053\u306e\u60c5\u5831\u306f\u3053\u306e\uff08\u307e\u305f\u306f\u4ed6\u306e\uff09\u75c5\u6c17\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3001\u907a\u4f1d\u306b\u3088\u3063\u3066\u5f71\u97ff\u3092\u53d7\u3051\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u591a\u69d8\u306a\u7d50\u679c\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u3053\u3053\u3067\u306f\u30e9\u30c6\u30f3\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u306b\u3064\u3044\u3066\u8a71\u3057\u307e\u3057\u305f\u304c\u3001\u30a2\u30d5\u30ea\u30ab\u3001\u30a4\u30f3\u30c9\u3001\u6771\u5357\u30a2\u30b8\u30a2\u306a\u3069\u3001\u4ed6\u306e\u3053\u308c\u307e\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3053\u306a\u304b\u3063\u305f\u4eba\u53e3\u96c6\u56e3\u3082\u8a72\u5f53\u3057\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u7cbe\u5bc6\u533b\u7642\u3084\u500b\u5225\u5316\u533b\u7642\u306b\u5411\u304b\u3046\u306b\u3042\u305f\u308a\u89e3\u6c7a\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u5927\u304d\u306a\u8ab2\u984c\u3067\u3059\u3002\u3053\u306e\u77e5\u8b58\u306e\u6b20\u5982\u306f\u3001\u65e2\u5b58\u306e\u5065\u5eb7\u683c\u5dee\u3092\u62e1\u5927\u3055\u305b\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n<p>\u5e78\u3044\u3001\u3053\u306e\u8ab2\u984c\u306b\u3064\u3044\u3066\u306e\u8a8d\u8b58\u306f\u9ad8\u307e\u3063\u3066\u304a\u308a\u3001\u72b6\u6cc1\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306e\u4e16\u754c\u7684\u306a\u53d6\u308a\u7d44\u307f\u306b\u62cd\u8eca\u304c\u304b\u304b\u3063\u3066\u3044\u307e\u3059\u3002Aligning Science Across Parkinson\u2019s\uff08ASAP\uff09\u306e\u30b0\u30ed\u30fc\u30d0\u30eb\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u907a\u4f1d\u5b66\u30d7\u30ed\u30b0\u30e9\u30e0\uff08GP2\uff09\u306f\u3001\u4e16\u754c\u4e2d\u306e\u7814\u7a76\u8005\u3092\u96c6\u3081\u3001PD\u306e\u907a\u4f1d\u7684\u69cb\u9020\u3092\u3055\u3089\u306b\u7406\u89e3\u3057\u3001\u7279\u306b\u3053\u308c\u307e\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3053\u306a\u304b\u3063\u305f\u4eba\u53e3\u96c6\u56e3\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u307e\u3059\u3002\u76ee\u6a19\u306f\u3001\u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab\u3001\u30ab\u30ea\u30d6\u6d77\u3001\u30a2\u30d5\u30ea\u30ab\u3001\u30a4\u30f3\u30c9\u3001\u6771\u5357\u30a2\u30b8\u30a2\u3001\u4e2d\u56fd\u3001\u304a\u3088\u3073\u7c73\u56fd\u306e\u5c11\u6570\u6c11\u65cf\u304b\u30895\u4e07\u4eba\u306e\u975e\u30e8\u30fc\u30ed\u30c3\u30d1\u4eba\u7a2e\u3092\u542b\u3080\u3001\u5c11\u306a\u304f\u3068\u308215\u4e07\u4eba\u306e\u65b0\u3057\u3044\u30dc\u30e9\u30f3\u30c6\u30a3\u30a2\u3092\u5bfe\u8c61\u306b\u7814\u7a76\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n<p>\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\u3092\u901a\u3058\u3066\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u591a\u69d8\u6027\u3092\u9ad8\u3081\u3001\u3053\u308c\u307e\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3053\u306a\u304b\u3063\u305f\u4eba\u53e3\u96c6\u56e3\u306e\u5065\u5eb7\u683c\u5dee\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u305f\u3081\u306b\u3001\u5927\u304d\u306a\u524d\u9032\u3092\u9042\u3052\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u53d6\u308a\u7d44\u307f\u306b\u305c\u3072\u53c2\u52a0\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><em>\u3053\u306e\u30d6\u30ed\u30b0\u6295\u7a3f\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3066\u304f\u308c\u305f\u30e1\u30bf\u30e9\u30dc\u306e\u65b0\u30e1\u30f3\u30d0\u30fcEmily Mason\u6c0f\u306b\u611f\u8b1d\u3057\u307e\u3059\u3002<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>GP2\u306f\u3001\u4eba\u53e3\u96c6\u56e3\u5168\u4f53\u3067\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u907a\u4f1d\u5b66\u306e\u7406\u89e3\u306b\u9769\u547d\u3092\u8d77\u3053\u3059\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002Ignacio &#8216;Nacho&#8217; Mata\u306f\u3001\u73fe\u5728\u75c5\u6c17\u306e\u7814\u7a76\u306b\u5341\u5206\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3044\u306a\u3044\u4eba\u3005\u3092\u5dfb\u304d\u8fbc\u3080\u3053\u3068\u306e\u91cd\u8981\u6027\u3092\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"author":0,"featured_media":50019539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50011815","post","type-post","status-publish","format-standard","hentry","post-type-gp2","post-type-720","topic-gp2-values-4"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50011815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/comments?post=50011815"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/posts\/50011815\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media\/50019539"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/ja\/wp-json\/wp\/v2\/media?parent=50011815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}