{"id":50012044,"date":"2023-08-25T20:35:41","date_gmt":"2023-08-26T00:35:41","guid":{"rendered":"https:\/\/gp2stg.wpenginepowered.com\/%d8%a7%d9%84%d8%b9%d9%84%d9%85-%d8%a7%d9%84%d8%aa%d8%b4%d8%a7%d8%b1%d9%83%d9%8a-%d9%8a%d9%82%d9%88%d8%af-%d9%84%d8%a7%d9%83%d8%aa%d8%b4%d8%a7%d9%81-%d8%ac%d9%8a%d9%86-gba1\/"},"modified":"2024-11-26T14:06:17","modified_gmt":"2024-11-26T19:06:17","slug":"%d8%a7%d9%84%d8%b9%d9%84%d9%85-%d8%a7%d9%84%d8%aa%d8%b4%d8%a7%d8%b1%d9%83%d9%8a-%d9%8a%d9%82%d9%88%d8%af-%d9%84%d8%a7%d9%83%d8%aa%d8%b4%d8%a7%d9%81-%d8%ac%d9%8a%d9%86-gba1","status":"publish","type":"post","link":"https:\/\/gp2.org\/ar\/%d8%a7%d9%84%d8%b9%d9%84%d9%85-%d8%a7%d9%84%d8%aa%d8%b4%d8%a7%d8%b1%d9%83%d9%8a-%d9%8a%d9%82%d9%88%d8%af-%d9%84%d8%a7%d9%83%d8%aa%d8%b4%d8%a7%d9%81-%d8%ac%d9%8a%d9%86-gba1\/","title":{"rendered":"\u0627\u0644\u0639\u0644\u0645 \u0627\u0644\u062a\u0634\u0627\u0631\u0643\u064a \u064a\u0642\u0648\u062f \u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u062c\u064a\u0646 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href=\"https:\/\/www.nature.com\/articles\/s41591-021-01672-4.epdf?sharing_token=4S_y467MybhxcXJ975aDDtRgN0jAjWel9jnR3ZoTv0MazbjTFAdIZAhM7O2cKQSpjl00XrWbFdEWbPkh3dLrfbCnd1qUYGlUVrk7KVMvgc0kT58VefY3A-NCtYyJotjPc4wQq3ek3fwM6kZkApDF8ntjmDAXrqyYJV9Iv3xSVOZAlUDELu8hBlobQH88loabUaCWaKQLlhNDiaC9b32zAg%3D%3D&amp;tracking_referrer=www.bbc.com\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> 86 <\/span><\/a><span style=\"font-weight: 400;\">\u0625\u0644\u0649 <\/span><a href=\"https:\/\/www.nature.com\/articles\/538161a\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">96<\/span><\/a><span style=\"font-weight: 400;\">%).<\/span><\/p>\n<p><span style=\"font-weight: 400;\"> \u00a0<\/span> <span style=\"font-weight: 400;\">\u0645\u0627 \u0647\u0648 \u0633\u064a\u0631 \u0627\u0644\u0639\u0645\u0644 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0627\u0644\u0630\u064a \u064a\u062a\u0645 \u062a\u0646\u0641\u064a\u0630\u0647\u061f \u064a\u0645\u0643\u0646 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\u0645\u0646 \u0631\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0641\u064a \u0642\u064a\u0627\u062f\u0629 \u0627\u0644\u0628\u0631\u0646\u0627\u0645\u062c \u0625\u0644\u0649 \u062a\u0645\u0648\u064a\u0644 \u062c\u0647\u0648\u062f \u0627\u0644\u062a\u062c\u0645\u064a\u0639 \u0641\u064a \u0627\u0644\u062f\u0648\u0644 \u0645\u062a\u062f\u0646\u064a\u0629 \u0648\u0645\u062a\u0648\u0633\u0637\u0629 \u0627\u0644\u062f\u062e\u0644 \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0627\u0644\u0633\u0643\u0627\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0645\u062b\u0644\u064a\u0646 \u0628\u0634\u0643\u0644 \u0643\u0627\u0641 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u00a0<\/span> <span style=\"font-weight: 400;\"> \u0648\u0641\u064a \u0627\u0644\u0639\u0627\u0645 \u0627\u0644\u0645\u0627\u0636\u064a\u060c \u062d\u0648\u0644 \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u062a\u0631\u0643\u064a\u0632\u0647 \u0645\u0646 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0648\u0627\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u062a\u062d\u062a\u064a\u0629 \u0625\u0644\u0649 \u062a\u0648\u0644\u064a\u062f \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a. \u0648\u0642\u062f \u062a\u0645 \u062a\u0646\u0641\u064a\u0630 \u0648\u0627\u062d\u062f \u0645\u0646 \u0627\u0644\u062a\u062d\u0627\u0644\u064a\u0644 \u0627\u0644\u062a\u0645\u0647\u064a\u062f\u064a\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0639\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0627\u0644\u0646\u064a\u062c\u064a\u0631\u064a\u064a\u0646. \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0648\u0642\u062a\u060c \u0627\u0639\u062a\u0628\u0631\u062a \u0647\u0630\u0647 \u0627\u0644\u062e\u0637\u0648\u0629 \u0628\u0645\u062b\u0627\u0628\u0629 \u0641\u0631\u0635\u0629 \u062a\u062f\u0631\u064a\u0628\u064a\u0629 \u062d\u0648\u0644 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629\u060c \u0641\u0627\u0644\u062a\u0648\u0642\u0639\u0627\u062a \u0643\u0627\u0646\u062a \u0645\u0646\u062e\u0641\u0636\u0629 \u0627\u0644\u0633\u0642\u0641 \u0646\u0638\u0631\u0627\u064b \u0644\u0635\u063a\u0631 \u062d\u062c\u0645 \u0627\u0644\u0639\u064a\u0646\u0629 (\u062d\u0648\u0627\u0644\u064a 1000 \u062d\u0627\u0644\u0629). \u0641\u064a \u0623\u063a\u0644\u0628 \u0627\u0644\u0623\u062d\u064a\u0627\u0646\u060c \u064a\u062a\u0631\u0627\u0648\u062d \u0639\u062f\u062f \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0648\u0627\u0633\u0639\u0629 \u0627\u0644\u0646\u0637\u0627\u0642 \u0645\u0646 \u0639\u0634\u0631\u0627\u062a \u0625\u0644\u0649 \u0645\u0626\u0627\u062a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0628\u0644 \u0648\u0642\u062f \u064a\u0635\u0644 \u0625\u0644\u0649 \u0627\u0644\u0622\u0644\u0627\u0641 \u0645\u0646\u0647\u0627 \u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0639\u0648\u0627\u0645\u0644 \u062e\u0637\u0631 \u062c\u064a\u0646\u064a\u0629 \u062c\u062f\u064a\u062f\u0629. \u0648\u0639\u0646\u062f\u0645\u0627 \u0627\u062a\u0636\u062d \u0628\u0623\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u062a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0627\u062d\u062a\u0645\u0627\u0644\u064a\u0629 \u0627\u0643\u062a\u0634\u0627\u0641 \u0645\u062a\u063a\u064a\u0631 \u062e\u0637\u0631 \u062c\u062f\u064a\u062f\u060c \u062a\u0645\u062a \u0625\u0639\u0627\u062f\u0629 \u062a\u0646\u0641\u064a\u0630 \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0644\u0631\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062b\u0642\u0629 \u062d\u0648\u0644 \u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0646\u062a\u0627\u0626\u062c. \u0648\u0645\u0646 \u062b\u0645 \u062a\u0645 \u0627\u0644\u062a\u0623\u0643\u062f \u0645\u0646 \u0635\u062d\u0629 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0628\u0648\u0627\u0633\u0637\u0629 \u062f\u0631\u0627\u0633\u0629 \u0645\u0633\u062a\u0642\u0644\u0629 \u0644\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0641\u064a <\/span><a href=\"https:\/\/www.centerwatch.com\/us\/en\/clinicaltrial\/260407\/black-and-african-american-connections-to-parkinsons-disease-blaac-pd-study\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">BLAAC-PD<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><b>\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0631\u0648\u0627\u0628\u0637 \u0628\u064a\u0646 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0630\u0648\u064a \u0627\u0644\u0628\u0634\u0631\u0629 \u0627\u0644\u0633\u0645\u0631\u0627\u0621<\/b><span style=\"font-weight: 400;\"> \u0648<\/span><b>\u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u064a\u0646 <\/b><span style=\"font-weight: 400;\">\u0645\u0646 \u0623\u0635\u0648\u0644 <\/span><b>\u0623\u0641\u0631\u064a\u0642\u064a\u0629 <\/b> <b><\/b><span style=\"font-weight: 400;\">\u0648<\/span><b>\u062f\u0627\u0621<\/b><span style=\"font-weight: 400;\"> \u0627\u0644\u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646<\/span><b><\/b><span style=\"font-weight: 400;\">)\u060c \u0648\u0647\u064a \u062c\u0647\u062f \u0645\u0634\u062a\u0631\u0643 \u064a\u062f\u0639\u0645\u0647 \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0628\u064a\u0646 \u0623\u0648\u0633\u0627\u0637 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0630\u064a\u0646 \u064a\u0646\u062d\u062f\u0631\u0648\u0646 \u0645\u0646 \u0623\u0635\u0648\u0644 \u0623\u0641\u0631\u064a\u0642\u064a\u0629 \u0648\u0645\u0646 \u0633\u0644\u0627\u0644\u0627\u062a \u0623\u0641\u0631\u064a\u0642\u064a\u0629 \u0645\u062e\u062a\u0644\u0637\u0629. \u0648\u0642\u062f \u062a\u0645 \u0627\u0644\u062a\u0648\u0635\u0644 \u0625\u0644\u0649 \u0646\u062a\u064a\u062c\u0629 \u0645\u0641\u0627\u062f\u0647\u0627 \u0623\u0646 \u0645\u062a\u063a\u064a\u0631 \u0627\u0644\u062e\u0637\u0631 \u0647\u0630\u0627 \u0645\u0646\u062a\u0634\u0631 \u0628\u064a\u0646 \u0627\u0644\u0633\u0643\u0627\u0646 \u0627\u0644\u0623\u0641\u0627\u0631\u0642\u0629 \u062e\u0627\u0631\u062c \u062d\u062f\u0648\u062f \u063a\u0631\u0628 \u0623\u0641\u0631\u064a\u0642\u064a\u0627.<\/span><\/p>\n<h4><b><i> \u0627\u0644\u0623\u062b\u0631 \u0648\u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0627\u0644\u0645\u0641\u062a\u0648\u062d\u0629 \u0648\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u062c\u062f\u064a\u062f\u0629<\/i><\/b><\/h4>\n<p><a href=\"https:\/\/www.thelancet.com\/journals\/laneur\/article\/PIIS1474-4422(23)00283-1\/fulltext\"><span style=\"font-weight: 400;\"> \u064a\u0624\u0643\u062f \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641<\/span><\/a><span style=\"font-weight: 400;\"> \u0639\u0644\u0649 \u0645\u0627 \u064a\u062d\u0645\u0644\u0647 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0627\u0644\u062c\u062f\u064a \u0628\u0627\u0644\u0639\u0644\u0645 \u0627\u0644\u0634\u0645\u0648\u0644\u064a\u060c \u0627\u0644\u0630\u064a \u064a\u0633\u0639\u0649 \u0625\u0644\u0649 \u0627\u0643\u062a\u0633\u0627\u0628 \u0627\u0644\u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629\u060c \u0645\u0646 \u0625\u0645\u0643\u0627\u0646\u064a\u0627\u062a \u0646\u062d\u0648 \u062a\u062d\u0633\u064a\u0646 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629. \u0644\u0645 \u064a\u0643\u064f\u0646 \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0645\u062a\u0648\u0642\u0639\u0627\u064b\u060c \u0648\u0644\u0643\u0646 \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u0642\u062f \u0646\u062c\u062d \u0641\u064a \u0625\u0646\u0634\u0627\u0621 \u0627\u0644\u0645\u0646\u0638\u0648\u0645\u0629 \u0648\u0627\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u062a\u062d\u062a\u064a\u0629 \u0627\u0644\u0644\u0627\u0632\u0645\u062a\u064a\u0646 \u0644\u0643\u064a \u0646\u0635\u0644 \u0625\u0644\u0649 \u0647\u0630\u0647 \u0627\u0644\u0623\u0646\u0648\u0627\u0639 \u0645\u0646 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641\u0627\u062a. \u064a\u0634\u0643\u0644 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0645\u0646 \u0630\u0648\u064a \u0627\u0644\u0623\u0635\u0648\u0644 \u0627\u0644\u0623\u0641\u0631\u064a\u0642\u064a\u0629 \u062d\u0648\u0627\u0644\u064a 2% \u0645\u0646 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0645\u0634\u0645\u0648\u0644\u064a\u0646 \u0641\u064a \u0623\u064a \u0646\u0648\u0639 \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0648\u0627\u0633\u0639\u0629 \u0627\u0644\u0646\u0637\u0627\u0642 [<\/span><a href=\"https:\/\/www.cell.com\/fulltext\/S0092-8674(19)30231-4\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sirugo et al., Cell 2019<\/span><\/a><span style=\"font-weight: 400;\">] \u0641\u064a \u0627\u0644\u0648\u0642\u062a \u0627\u0644\u0630\u064a \u064a\u0634\u0643\u0644\u0648\u0646 \u0641\u064a\u0647 \u0645\u0627 \u0646\u0633\u062a\u0628\u0647 18% \u0645\u0646 \u0633\u0643\u0627\u0646 \u0627\u0644\u0639\u0627\u0644\u0645. \u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u0644\u0637\u0627\u0644\u0645\u0627 \u0627\u0639\u062a\u0628\u0631 \u062f\u0627\u0621 \u0627\u0644\u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 \u0623\u0642\u0644 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b \u0628\u064a\u0646 \u0623\u0648\u0633\u0627\u0637 \u0627\u0644\u0633\u0643\u0627\u0646 \u0627\u0644\u0623\u0641\u0627\u0631\u0642\u0629 \u0648\u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u064a\u0646 \u0645\u0646 \u0623\u0635\u0648\u0644 \u0623\u0641\u0631\u064a\u0642\u064a\u0629 (Bailey et al, 2020, Okubadejo 2007). \u0648\u062a\u064f\u0639\u0651\u062f \u0647\u0630\u0647 \u0627\u0644\u0645\u0632\u0627\u0639\u0645 \u0645\u062b\u064a\u0631\u0629 \u0644\u0644\u062c\u062f\u0644\u060c \u062d\u064a\u062b \u062a\u0648\u062c\u062f \u0641\u064a \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0623\u062d\u064a\u0627\u0646 \u062a\u0642\u0627\u0631\u064a\u0631 \u062a\u062f\u062d\u0636\u0647\u0627\u060c \u0643\u0645\u0627 \u0623\u0646 \u0647\u0646\u0627\u0643 \u0627\u0644\u0642\u0644\u064a\u0644 \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0634\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0627\u0644\u0633\u0643\u0627\u0646\u064a\u0629 \u0628\u0627\u0644\u0623\u0633\u0627\u0633. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u00a0<\/span> <span style=\"font-weight: 400;\">\u0628\u0635\u0641\u062a\u064a \u0627\u0645\u0631\u0623\u0629 \u0630\u0627\u062a \u0628\u0634\u0631\u0629 \u0633\u0648\u062f\u0627\u0621 \u0645\u0646 \u0623\u0635\u0648\u0644 \u0646\u064a\u062c\u064a\u0631\u064a\u0629\u060c \u0641\u0625\u0646 \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u064a\u0645\u0633\u0646\u064a \u0634\u062e\u0635\u064a\u0627\u064b. \u0641\u064a \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0623\u062d\u064a\u0627\u0646\u060c \u0644\u0627 \u0623\u062c\u062f \u0646\u0641\u0633\u064a \u0645\u0645\u062b\u0644\u0629 \u0643\u0645\u0627 \u064a\u0646\u0628\u063a\u064a \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0628\u062d\u062b\u064a\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629\u060c \u0645\u0627 \u064a\u062c\u0639\u0644 \u0627\u0644\u0627\u0646\u062e\u0631\u0627\u0637 \u0639\u0646 \u0643\u062b\u0628 \u0641\u064a \u0627\u0643\u062a\u0634\u0627\u0641 \u0644\u0647 \u062a\u062f\u0627\u0639\u064a\u0627\u062a\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0639\u0644\u0649 \u0645\u062c\u062a\u0645\u0639\u064a \u0648\u0643\u0644 \u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0645\u0646\u062d\u062f\u0631\u064a\u0646 \u0645\u0646 \u0633\u0644\u0627\u0644\u0627\u062a \u0645\u0634\u0627\u0628\u0647\u0629 \u0623\u0645\u0631\u0627\u064b \u0645\u0631\u0636\u064a\u0627\u064b \u0628\u0634\u0643\u0644 \u0627\u0633\u062a\u062b\u0646\u0627\u0626\u064a. \u0648\u0641\u064a \u0627\u0644\u0648\u0642\u062a \u0627\u0644\u0630\u064a \u0623\u0636\u062d\u062a \u0641\u064a\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0648\u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0623\u0643\u062b\u0631 \u0634\u064a\u0648\u0639\u0627\u064b\u060c \u064a\u064f\u0635\u0628\u062d \u0645\u0646 \u0627\u0644\u0636\u0631\u0648\u0631\u064a \u062a\u0642\u0644\u064a\u0635 \u0641\u062c\u0648\u0629 \u0627\u0644\u062a\u0646\u0648\u0639 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u0643\u0628\u064a\u0631\u0629\u060c \u0641\u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0628\u0628\u0639\u0636 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0642\u062f \u0644\u0627 \u062a\u0635\u0644\u062d \u0644\u0643\u0644 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0625\u062b\u0646\u064a\u0629\u060c \u0643\u0645\u0627 \u0623\u062b\u0628\u062a \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0645\u0646 \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u0648\u063a\u064a\u0631\u0647 \u0645\u0646 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641\u0627\u062a \u0641\u064a \u0645\u062c\u0627\u0644\u0627\u062a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 (\u0645\u062b\u0644 \u0645\u062a\u063a\u064a\u0631\u0627\u062a<\/span><i><span style=\"font-weight: 400;\"> CYP2D6 <\/span><\/i><span style=\"font-weight: 400;\">\u0627\u0644\u062a\u064a \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0641\u064a \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u062f\u0648\u0627\u0621 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 [tamoxifen] \u0628\u064a\u0646 \u0623\u0648\u0633\u0627\u0637 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0633\u0643\u0627\u0646\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 [<\/span><a href=\"https:\/\/www.nature.com\/articles\/538161a\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Popejoy &amp; Fullerton. Nature 2016<\/span><\/a><span style=\"font-weight: 400;\">] \u0648\u0627\u0644\u062a\u0637\u0648\u0631\u0627\u062a \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u0647\u062f\u0641 \u0627\u0644\u0643\u0648\u0644\u0633\u062a\u0631\u0648\u0644 [ \u0645\u062b\u0628\u0637\u0627\u062a<\/span><i><span style=\"font-weight: 400;\">PCSK9<\/span><\/i><span style=\"font-weight: 400;\"> ] \u0627\u0644\u062a\u064a \u062c\u0627\u0621\u062a \u0646\u062a\u064a\u062c\u0629 \u0634\u0645\u0648\u0644 \u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u064a\u0646 \u0645\u0646 \u0623\u0635\u0648\u0644 \u0623\u0641\u0631\u064a\u0642\u064a\u0629 \u0641\u064a \u0627\u0644\u0623\u0628\u062d\u0627\u062b [<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15654334\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cohen et al., Nat Gen 2005<\/span><\/a><span style=\"font-weight: 400;\">]). \u064a\u0642\u062f\u0645 \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0641\u0631\u0635\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u0645\u0646\u062d\u062f\u0631\u064a\u0646 \u0645\u0646 \u0623\u0635\u0648\u0644 \u0623\u0641\u0631\u064a\u0642\u064a\u0629.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u0628\u064a\u062f \u0623\u0646 \u0647\u0646\u0627\u0643 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u062d\u0648\u0644 \u0643\u064a\u0641\u064a\u0629 \u0645\u0633\u0627\u0647\u0645\u0629 \u062c\u064a\u0646<\/span><i><span style=\"font-weight: 400;\"> GBA1 <\/span><\/i><span style=\"font-weight: 400;\">\u0641\u064a \u062f\u0627\u0621 \u0627\u0644\u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 \u0645\u0627 \u062a\u0632\u0627\u0644 \u062a\u0646\u062a\u0638\u0631 \u0627\u0644\u0625\u062c\u0627\u0628\u0629. \u0628\u0639\u062f \u0625\u062c\u0631\u0627\u0621 \u0634\u0631\u0643\u0629 \u0633\u0627\u0646\u0648\u0641\u064a \u0644\u0648\u0627\u062d\u062f\u0629 \u0645\u0646 \u0623\u0648\u0644\u0649 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u062a\u064a \u0627\u0633\u062a\u0647\u062f\u0641\u062a \u062c\u064a\u0646<\/span><i><span style=\"font-weight: 400;\"> GBA1 <\/span><\/i><span style=\"font-weight: 400;\"> (Venglustat)\u060c \u0643\u0627\u0646\u062a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37479372\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u064f\u0639\u0627\u0644\u062c\u0629 \u0641\u064a \u062d\u0627\u0644\u0629 \u0623\u0633\u0648\u0623 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629<\/span><\/a><span style=\"font-weight: 400;\">\u060c \u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0641\u0647\u0645 \u0633\u064a\u0626 \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0645\u064a\u0643\u0627\u0646\u064a\u0643\u064a\u0629 \u0644\u0622\u0644\u064a\u0629 \u0639\u0645\u0644 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0641\u0639\u0644\u064a\u0629. \u0648\u0645\u0646 \u062e\u0644\u0627\u0644 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0645\u062a\u063a\u064a\u0631\u0627\u062a \u062c\u064a\u0646 <\/span><i><span style=\"font-weight: 400;\"> GBA1 <\/span><\/i><span style=\"font-weight: 400;\">\u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0645\u0631\u0636\u060c \u064a\u0645\u0643\u0646\u0646\u0627 \u062a\u062d\u0633\u064a\u0646 \u0641\u0647\u0645\u0646\u0627 \u0644\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u062a\u064a \u062a\u0624\u062f\u064a \u0628\u0647\u0627 \u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0647\u0630\u0627 <\/span><i><span style=\"font-weight: 400;\">\u0627\u0644\u062c\u064a\u0646 <\/span><\/i><span style=\"font-weight: 400;\">\u0625\u0644\u0649 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0645\u0631\u0636 \u0648\u062a\u062d\u0633\u064a\u0646 \u0627\u0633\u062a\u0647\u062f\u0627\u0641 \u0627\u0644\u0645\u0642\u0627\u0631\u0628\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0644\u0647\u0630\u0627 \u0627\u0644\u0645\u0633\u0627\u0631 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0647. \u0645\u0646 \u0627\u0644\u0645\u0647\u0645 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0647\u0646\u0627 \u0625\u0644\u0649 \u0623\u0646\u0647 \u0648\u0645\u0646 \u062e\u0644\u0627\u0644 \u062f\u0631\u0627\u0633\u0629 \u0647\u0630\u0647 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0641\u064a \u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0633\u0643\u0627\u0646\u064a\u0629 \u0645\u062e\u062a\u0644\u0641\u0629 \u062d\u0648\u0644 \u0627\u0644\u0639\u0627\u0644\u0645\u060c \u064a\u064f\u0645\u0643\u0646\u0646\u0627 \u062a\u0648\u0633\u064a\u0639 \u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0645\u0643\u0646\u0647\u0645 \u0627\u0644\u0627\u0633\u062a\u0641\u0627\u062f\u0629 \u0645\u0646 \u0627\u0644\u0645\u0642\u0627\u0631\u0628\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u0647\u062f\u0641 \u062c\u064a\u0646<\/span><i><span style=\"font-weight: 400;\"> GBA1<\/span><\/i><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\"> <span style=\"font-weight: 400;\"> \u0648\u0628\u064a\u0646\u0645\u0627 \u064a\u0633\u062a\u0645\u0631 \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u0628\u062a\u0633\u0631\u064a\u0639 \u0639\u062c\u0644\u0629 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641\u0627\u062a\u060c \u0646\u062a\u0648\u0642\u0639 \u0628\u0623\u0646 \u062a\u0638\u0647\u0631 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0641\u064a \u0627\u0644\u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0627\u0644\u0633\u0643\u0627\u0646\u064a\u0629 \u062d\u0648\u0644 \u0627\u0644\u0639\u0627\u0644\u0645\u060c \u0648\u0627\u0644\u062a\u064a \u0645\u0646 \u0634\u0623\u0646\u0647\u0627 \u0623\u0646 \u062a\u063a\u064a\u0631 \u0645\u0642\u0627\u0631\u0628\u062a\u0646\u0627 \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0625\u062b\u0631\u0627\u0621 \u0641\u0647\u0645\u0646\u0627 \u0644\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0644\u062f\u0627\u0621 \u0627\u0644\u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646. \u0648\u0625\u0630\u0627 \u0645\u0627 \u062a\u0623\u0645\u0644\u0646\u0627 \u0641\u064a \u0627\u0644\u0645\u0646\u0638\u0648\u0645\u0629 \u0627\u0644\u062a\u064a \u0646\u062c\u062d \u0628\u0631\u0646\u0627\u0645\u062c GP2 \u0641\u064a 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<\/span><\/span><\/p>\n<p><span style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">\u00a0<\/span> <span style=\"font-weight: 400;\"> \u062a\u0631\u0642\u0628\u0648\u0627 \u0645\u0633\u062a\u062c\u062f\u0627\u062a \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0646\u0627\u0645\u062c\u060c \u0641\u0645\u0627 \u064a\u0632\u0627\u0644 \u0647\u0646\u0627\u0643 \u0627\u0644\u0645\u0632\u064a\u062f! <\/span><\/span><\/p>\n<p><span style=\"font-weight: 400;\"> <span class=\"ui-provider cij cik c d e f g h i j k l m n o p q r s t cil cim w x y z ab ac ae af ag ah ai aj ak\" dir=\"ltr\"> (\u0625\u062e\u0644\u0627\u0621 \u0645\u0633\u0624\u0648\u0644\u064a\u0629: \u064a\u064f\u0639\u0651\u064e\u062f \u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u062e\u0637\u0648\u0629 \u0645\u0641\u0635\u0644\u064a\u0629 \u0647\u0627\u0645\u0629 \u0641\u064a \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0647\u0627\u062f\u0641\u0629 \u0644\u062f\u0631\u0627\u0633\u0629 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title=\"https:\/\/protect-eu.mimecast.com\/s\/rcn6cx7edtmzqookc6_vrg?domain=michaeljfox.org\" href=\"https:\/\/protect-eu.mimecast.com\/s\/Rcn6CX7EDTMZQOokc6_VRg?domain=michaeljfox.org\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Link \">\u0627\u0642\u0631\u0623 \u0647\u0630\u0647 \u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0634\u064a\u0648\u0639\u0627\u064b <\/a>\u0644\u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u062d\u0648\u0644 \u0627\u0644\u0623\u062b\u0631 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0644\u0647\u0630\u0627 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0643).<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0623\u0648\u0644 \u0627\u0643\u062a\u0634\u0627\u0641 \u0645\u0647\u0645 \u0644\u0639\u0627\u0645\u0644 \u062c\u062f\u064a\u062f \u0645\u0646 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062e\u0637\u0631 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[&hellip;]<\/p>\n","protected":false},"author":16,"featured_media":50024690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-50012044","post","type-post","status-publish","format-standard","hentry","post-type-745","post-type-729","post-type-750","post-type--gp2","topic-gp2-values-5","topic-research-collaboration-2"],"acf":[],"_links":{"self":[{"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/posts\/50012044","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/comments?post=50012044"}],"version-history":[{"count":0,"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/posts\/50012044\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/media\/50024690"}],"wp:attachment":[{"href":"https:\/\/gp2.org\/ar\/wp-json\/wp\/v2\/media?parent=50012044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}